JMdict

ネガティブ

読み方：ネガチブ、ネガチィブ、ネガティヴ

（形容動詞／ナ形容詞、名詞） negative （※対義語：ポジティブ）

機械工学英和和英辞典

ネガティブ（負の，マイナスの，陰電気の）

negative

ライフサイエンス辞書

ネガティブ

***** ねがてぃぶ

(aj) negative ****

(adv) negatively ****

関連語

陰性, 負, 否定的

用例

negative [負の]

There was a negative correlation between the concentration of nitrite in cerebrospinal fluid and the degree of cerebral vasospasm (P<.001). (JAMA)

Myostatin is an endogenous, negative regulator of muscle growth. (Curr Opin Rheumatol)

X-negative [〜陰性]

Genome-wide measures of gene expression can identify patterns of gene activity that subclassify tumours and might provide a better means than is currently available for individual risk assessment in patients with lymph-node-negative breast cancer. (Lancet)

MuSK antibodies are found in a variable proportion of AChR antibody negative myasthenia gravis patients who are often, but not exclusively, young adult females, with bulbar, neck, or respiratory muscle weakness. (Curr Opin Neurol)

gram-negative [グラム陰性]

Autotransporter proteins are a large family of gram-negative bacterial extracellular proteins. (Trends Microbiol)

By inhibiting bacterial cell wall synthesis, they are highly effective against Gram-positive and Gram-negative bacteria. (Curr Opin Microbiol)

false-negative [偽陰性]

The same isolates from SDA tested for RAT produced six false negatives and no false positives (sensitivity, 81%; specificity, 100%). (J Clin Microbiol)

The false negative rate was the highest (85.7%) for exons with low frequencies of transcript inclusion. (Bioinformatics)

A low dose was the only statistically significant (P < .001) risk factor for a false-negative result. (Radiology)

This should serve to greatly decrease the likelihood of false positive and false negative findings reported in future years. (Hum Mol Genet)

negative charge [負電荷]

Several innovative prodrug derivatizations have also been reported to improve the oral bioavailability of nucleotide analogs, which usually carry a negative charge. (Curr Opin Pharmacol)

be negative with [〜が陰性である]

In situ hybridization for Epstein Barr virus revealed rare positive lymphoid cells, that were negative with CD3 by immunohistochemical staining. (Transplantation)

negative control [負の対照，ネガティブコントロール]

Since red blood cells do not express MHC, they were used as a negative control. (Anal Biochem)

Ten pigs in group 1 received phosphate-buffered saline as negative controls. (J Virol)

dominant-negative [ドミナントネガティブな]

Dominant-negative FAK and Fyn mutants inhibited the attractive turning response to netrin. (Nat Neurosci)

In addition to ARF deletion, p53 pathway disruption can result from dominant negative TP53 mutations. (Nat Genet)

This response is thought to be a quality-control mechanism that protects cells from truncated dominant-negative proteins. (Trends Genet)

negative feedback [負のフィードバック]

Activation of PKA may constitute a negative-feedback mechanisms for lowering cAMP levels. (Proc Natl Acad Sci USA)

It is expected that their activation would provide negative feedback to transmitter release, but the opposite is sometimes observed. (J Neurosci)

Voltage-gated Ca2+ channels undergo a negative feedback regulation by Ca2+ ions, Ca2+-dependent inactivation, which is important for restricting Ca2+ signals in nerve and muscle. (J Biol Chem)

An increase in circulating glucose inhibits glucose production in the liver, but this negative feedback is impaired in type 2 diabetes. (Science)

negative staining [ネガティブ(逆)染色]

Electron microscopy using negative staining revealed that the addition of ATP induces a large conformational change in the neck/tail region of the expressed molecule. (EMBO J)

Using a negative staining approach, maltose phosphorylase, a phosphate-consuming enzyme, can also be detected. (Anal Biochem)

negative cooperativity [負の協同性]

ATP binding is characterized by significantly stronger negative cooperativity than ADP. (Biochemistry)

This indicates negative cooperativity for ligand binding between subunits. (J Mol Biol)

用例

negatively [ネガティブに，負に]

Furthermore, both IL-4 and interferon-gamma negatively regulated T helper cell production of IL-17 in the effector phase. (Nat Immunol)

We show that genome size is negatively correlated with genetic variability, independent of phylogeny, body size and generation time. (Trends Genet)

In contrast, altering Ser129 to the negatively charged residue aspartate, to mimic phosphorylation, significantly enhances alpha-synuclein toxicity. (Nat Neurosci)

be negatively regulated by [〜によって負の制御を受ける]

The gal operon of Escherichia coli is negatively regulated by repressor binding to bipartite operators separated by 11 helical turns of DNA. (Proc Natl Acad Sci USA)

In higher eukaryotes, the cyclin-dependent kinases are negatively regulated by phosphorylation on threonine 14 and tyrosine 15. (EMBO J)

The activity of the pathway is negatively regulated by overexpression of a SOCS protein and by blocking endocytosis. (Development)

negativeの共起表現

negativelyの共起表現

日本語WordNet(英和)

ネガティブ

【形容詞】

1 inactive, passive

行動力または意志が欠けている

(lacking in energy or will)

Much benevolence of the passive order may be traced to a disinclination to inflict pain upon oneself- George Meredith 受動的な教団の多くの慈悲心が、自分自身に苦痛を与える嫌気に由来するかもしれない−ジョージ・メレディス

2 negative

否定、拒絶、あるいは否認を表すか、から成るさま

(expressing or consisting of a negation or refusal or denial)

3 negative

否定、否認、反対または抵抗により特徴付けられるか、または示すさま

(characterized by or displaying negation or denial or opposition or resistance)

a negative outlook on life ネガティブな人生観 a colorless negative personality 生気のない否定的な個性 a negative evaluation 否定的な評価 a negative reaction to an advertising campaign 広告キャンペーンへの否定的な反応

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