研究社 新和英中辞典

あっか^１ 悪化

〈状態の〉 a change for the worse; 【形式ばった表現】 (a) deterioration

〈風俗などの〉 corruption; 【形式ばった表現】 degeneration

悪化する

get [【形式ばった表現】 become] worse; go from bad to worse; 【形式ばった表現】 deteriorate

〈病状が〉 take a turn for the worse

〈事態が〉 grow more serious

悪化させる

make something worse

【形式ばった表現】 aggravate

用例

情勢は急速に悪化していた. The situation was fast deteriorating.

斎藤和英大辞典

悪化

読み方 あっか

名詞

Deterioration; degeneration:（=する）to deteriorate; to degenerate

用例

花は培養しないと悪化してもとの雑草にかえる
Flowers, it left uncultivated, degenerate into weeds.

JMdict

悪化

読み方：あっか

あっ化 とも書く

（名詞、サ変名詞、形容詞相当語句／ノ形容詞） (suffer) deterioration; growing worse; aggravation; degeneration; corruption

英和生命保険用語辞典

悪化

downturn

学術用語英和対訳集

悪化

deterioration

JST科学技術用語日英対訳辞書

悪化

deterioration; worsening; aggravation

英和医学用語集

悪化

deterioration，aggravation，exasperation

ライフサイエンス辞書

悪化

***** あっか

(n) deterioration ***

(n) exacerbation ***

(n) aggravation **

(n) exaggeration **

(v) worsen ***

(vt) exacerbate ****

(vt) aggravate ***

(vt) exaggerate ***

(v) deteriorate ***

関連語

増悪, 痴呆, 変質, 劣化, 誇張

用例

deterioration [変性，悪化]

Infantile Krabbe's disease produces progressive neurologic deterioration and death in early childhood. (N Engl J Med)

Therefore, treating hypertension and protecting the kidney from deterioration are exceedingly important. (Curr Opin Cardiol)

deterioration [荒廃(痴呆)]

Severe hypoxemia can lead to clinical deterioration. (Gastroenterology)

Hyponatremia and increasing body temperature may be related to clinical deterioration. (N Engl J Med)

deterioration in [〜における悪化(荒廃)]

Findings suggest that the dog, like other species, shows age-dependent deterioration in cognitive function. (Behav Neurosci)

All treatments showed both improvement and deterioration in 3-14% and 0-16% of patients, respectively. (Lancet)

About 86% of participants reported a deterioration in their health status after nephrectomy. (JAMA)

用例

exacerbation [増悪]

Omalizumab reduced exacerbation rates, improved asthma symptoms and quality of life, and allowed lower doses of inhaled steroid compared with placebo. (Lancet)

Reports of asthma exacerbations in vaccinees with prior asthma history highlight the risks of vaccine use inconsistent with approved labeling. (JAMA)

An exacerbation of Wegener granulomatosis was the principal concern because of the frequency of flares in that disease. (JAMA)

acute exacerbation of [〜の急性憎悪]

Little randomized evidence is available to guide the in-hospital management of patients with an acute exacerbation of chronic heart failure. (JAMA)

用例

worsen [悪化させる]

Obesity and high neutrophil counts also worsened the PM effects with or without GSTM1. (Am J Respir Crit Care Med)

A progressive increase in QRS duration worsens the prognosis. (J Am Coll Cardiol)

用例

X-exacerbated [〜が悪化させた]

The prevalence of aspirin-exacerbated respiratory tract disease is approximately 10% and for aspirin-induced urticaria the prevalence varies from 0.07% to 0.2% of the general population. (JAMA)

exacerbated [増悪した，悪化した]

How exacerbated Na(+) channel activity elicits a toxic rise in cytoplasmic Ca(2+), however, has remained unclear. (Nat Neurosci)

be exacerbated by [〜によって増悪する]

We therefore hypothesized that pain might be exacerbated by proinflammatory chemokines. (Proc Natl Acad Sci USA)

The growth defect within macrophages was exacerbated by treatment of the host cells with an iron chelator. (Infect Immun)

用例

aggravate [悪化させる]

Ischemic stroke is often accompanied by neuronal hyperexcitability (i.e., seizures), which aggravates brain damage. (J Neurosci)

Hypercholesterolemia (HC) and atherosclerosis often accompany and aggravate renal disease. (J Am Soc Nephrol)

aggravated by [〜によって悪化される]

A 'brain-skin connection' with local neuroimmunoendocrine circuitry underlies the pathogenesis of allergic and inflammatory skin diseases, triggered or aggravated by stress. (Trends Immunol)

We conclude that physiological stresses (not necessarily genotoxic) aggravated by smoking are the leading risk factor in the p53-associated etiology of lung cancer. (Proc Natl Acad Sci USA)

be aggravated by [〜によって悪化する]

Skeletal muscle insulin resistance may be aggravated by intramyocellular accumulation of fatty acid-derived metabolites that inhibit insulin signaling. (J Biol Chem)

These changes may be aggravated by atherosclerosis, hypertension, or diabetes, which are highly prevalent in older individuals. (Transplantation)

用例

exaggerate [誇張する，(病気を)悪化させる]

Data are often presented using formats that may exaggerate the perceived importance of findings. (JAMA)

Furosemide exaggerates these losses, whereas its combination with spironolactone attenuates these responses to prevent bone loss. (J Am Coll Cardiol)

There is a significant pharmacokinetic interaction between capecitabine and S-warfarin, resulting in exaggerated anticoagulant activity. (J Clin Oncol)

用例

deteriorate [悪化する，変質する]

Although several controversies remain, it is clear that images deteriorate. (Proc Natl Acad Sci USA)

In Ringer's solution, the damaged cells deteriorated completely within 1 hr. (Proc Natl Acad Sci USA)

ATP production was impaired and continued to deteriorate with age. (J Biol Chem)

The aging process imposes a threat to diversity, because thymic function deteriorates. (J Immunol)

We hypothesized that the progression of atherosclerosis coincides with the deteriorating repair capacity of the bone marrow. (Proc Natl Acad Sci USA)

deteriorationの共起表現

exacerbationの共起表現

aggravationの共起表現

exaggerationの共起表現

exacerbateの共起表現

aggravateの共起表現

exaggerateの共起表現

日本語WordNet(英和)

悪化

【動詞】

1 degenerate, devolve, deteriorate, drop

悪くなる

(grow worse)

Her condition deteriorated 彼女の状態は悪化した Conditions in the slums degenerated スラムの状態は悪化していた The discussion devolved into a shouting match 議論は、叫び合いへと変化していった

2 worsen, decline

悪くなる

(grow worse)

Conditions in the slum worsened スラムの状態は悪化した

3 relapse, get worse

健康が衰える

(deteriorate in health)

he relapsed 彼は再発した

【名詞】

1 aggravation, exacerbation

ある問題や病気（またはその症状）をより悪くする行為

(action that makes a problem or a disease (or its symptoms) worse)

the aggravation of her condition resulted from lack of care 彼女の状態の悪化は、不注意からきている

2 exacerbation

激しくひどく憤慨させること

(violent and bitter exasperation)

his foolishness was followed by an exacerbation of their quarrel 彼らの口論の悪化によって、彼の愚かさが分かった

3 worsening, deterioration, decline in quality, declension

劣った状態へと変化する過程

(process of changing to an inferior state)

4 deterioration, impairment

品質や強さが減少する兆し

(a symptom of reduced quality or strength)

>>「悪化」に関する類語一覧

日英・英日専門用語辞書

悪化

depravation，debasement，deterioration，exacerbation，exacerbate，aggravate，deleterious change，deteriorate，aggravation

クロスランゲージ 37分野専門語辞書

悪化

debasement; exacerbation; getting worse; aggravation; deleterious change; worsening; change for the worse; deterioration; downturn