細気管支肺胞上皮癌の英語

②日本バイオアッセイ研究センターの長期がん原性試験結果では、雌雄のラットに104週間、0.01、0.03、0.1mg/m3濃度でITO研削粉をばく露させた結果、最低濃度の0.01mg/m3において肺に細気管支－肺胞上皮癌及び細気管支－肺胞上皮腺腫の発生増加が認められ、さらに、雄では肺に腺扁平上皮癌、雌では肺に腺扁平上皮癌と扁平上皮癌も認められた。例文帳に追加

② In the carcinogenicity study by Japan Bioassay Research Center, rats of both sexes were exposed to the 0.01, 0.03 and 0.1mg/m3 concentrations of ITO grinding dusts for 104 weeks.Growth and proliferation of small bronchial-alveolar cell carcinoma and small bronchial-alveolar epithelial adenoma were observed in the lungs of rats at the minimum concentration of 0.01mg/m3 . - 厚生労働省

喀痰や気管支鏡検査による洗浄細胞診や生体組織診によって得られた気管支上皮内の芳香族炭化水素レセプター（ＡｈＲ）およびチトクローム解毒酵素Ｐ４５０（ＣＹＰ）２Ａ６・ＣＹＰ２Ｅ１・ＣＹＰ１Ａ１の何れか一方または双方の発現量をＲＮＡレベル、蛋白質レベルで検出して被検者の肺癌感受性を検出する。例文帳に追加

Lung cancer sensibility of a subject is detected, by detecting the developed quantities of either one of or both of the aromatic hydrocarbon receptor (AhR), cytochrome detoxifying enzymes P450(CYP)2A6, CYP2E1 and CYP1A1 in the bronchial epithelium, which are obtained by washing cytodiagnosis or biopsy by examining sputum or by bronchoscopy, on an RNA (ribonucleic acid) level and a protein level. - 特許庁