「receptors」の共起表現(1語右で並び替え)

「receptors」の共起表現一覧(1語右で並び替え)

receptors

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to PPARs (peroxisome proliferator-activated receptors), a group of receptor molecules inside the c
nably selective antagonist for the adenosine receptors A1 and A2A, having a Ki of 3.3nM at A2A and
ntagonism of presynaptic inhibitory dopamine receptors accounting for some antidepressant activity
M2 muscarinic receptors act via a Gi type receptor, which causes a d
ective mixed agonist-antagonist for dopamine receptors, acting as a weak partial agonist at the D3
onist at α4β2 neural nicotinic acetylcholine receptors, acting as an agonist at (α4)2(β2)3 pentamer
Tyrosine kinase growth factor receptors activate mitogen-activated protein kinases w
1 over D5 with negligible affinity for other receptors; acts as an antagonist at D1 but as an agoni
There are three type I Activin receptors: ACVR1, ACVR1B, and ACVR1C.
inding domain of HNF4, as with other nuclear receptors, adopts a canonical alpha helical sandwich f
The receptors affect the downstream target AMP kinase, an
Retrovirus receptors allow infection of human and murine cells by
s along with the five different somatostatin receptors allows somatostatin to possess a large range
ptor antagonist, antagonizing A1, A2, and A3 receptors almost equally, which explains many of its c
Increased firing from the stretch receptors also increases production of pulmonary surfa
Receptors also have varying affinities for odorant mol
However, metabotropic receptors also remain open from seconds to minutes (Ka
ally show no affinity for the most important receptors, although modulation of most important centr
nd anxiolytic effects is by modulating GABAA receptors, although suriclone is more subtype-selectiv
ide antagonist selective for the neurotensin receptors, although not selective between subtypes.
ts anxiolytic effects is by modulating GABAA receptors, although ocinaplon is more subtype-selectiv
t but non-selective partial agonist at GABAA receptors, although with little efficacy at the α1 sub
Like capsaicin, capsinoids activate TRPV1 receptors, although they are not hot in the mouth.
as a partial agonist at GABAA benzodiazepine receptors, although pazinaclone is more subtype-select
tragynine itself acts primarily via μ-opioid receptors, although its oxidation product mitragynine-
moniae that seemed to involve an exchange of receptors among diverse bacteria either grown together
teins (RAMPs), forming the multimeric amylin receptors AMY1 (CT + RAMP1), AMY2 (CT + RAMP2), and AM
with around 70x selectivity for OX1 over OX2 receptors, and improved oral bioavailability compared
h show little or no affinity to other opioid receptors and so allow ORL-1 mediated responses to be
rect or indirect activation of CB2 and TRPV1 receptors, and induction of oxidative stress, all cont
onsidered a full agonist at both CB1 and CB2 receptors and has Ki values of 0.58nM and 0.68nM respe
ive in synthesizing shape- and ion-selective receptors, and throughout the 1980s research in the ar
ntaining a striped expression pattern of Eph receptors and their ligands, which is vital to proper
properties (potentiation of interferon gamma receptors and production), DIM is also under investiga
a subtype-selective partial agonist at GABAA receptors, and was developed by Pfizer as a potential
It has been found to inhibit histamine H1 receptors and platelet aggregation, and acts as an opi
as, , had a direct action at pharmacological receptors and thereby acting as a neurotransmitter was
the fact that it has high affinity for both receptors and stimulates the D5-linked PLC/PI second m
rovides a liver with normally functional LDL receptors, and leads to rapid improvement of the chole
acts as an agonist at the 5-HT1A and 5-HT1B receptors and as an antagonist at the 5-HT2C receptor.
receptor, a weak agonist at both CB1 and CB2 receptors, and an inhibitor of anandamide reuptake.
partial agonist action at Alpha-2 adrenergic receptors, and TDIQ has been suggested as a possible d
(dPTX) is most effective to block glutamate receptors and especially those quisqualate-sensitive,
t adenylate cyclases may couple to olfactory receptors and that there may be multiple receptor-medi
ive for the ORL-1 receptor over other opioid receptors, and its effects in animals include preventi
cid binding Ig-like lectins are cell surface receptors and members of the immunoglobulin superfamil
eline, an agonist on Ganglion type nicotinic receptors and also affects sensory nerve terminals
ation that inhibits muscarinic acetylcholine receptors and thus the parasympathetic nervous system.
pericine has been shown to bind to mu opioid receptors, and has an IC50 of 0.6μmol, around 6x more
specialize in binding to erythrocyte surface receptors and facilitating erythrocyte entry.
ptor β is a member of the family of estrogen receptors and the superfamily of nuclear receptor tran
th either GRIK4 or GRIK5 to form heteromeric receptors and acts as an excitatory neurotransmitter a
rations actually prevent dimerization of the receptors and prevent signalling.
d imidazoline binding sites, and blocks NMDA receptors and other cation ligand-gated channels.
Quisqualic acid is an agonist for both AMPA receptors and group I metabotropic glutamate receptors
of agonists acting through G protein-coupled receptors and receptor tyrosine kinases stimulate this
an agonist at neural nicotinic acetylcholine receptors and has been researched for use as an analge
These saturate the receptors and prevent T cell activation and thus preve
gerol as a high affinity agonist for alpha-2 receptors and a medium affinity antagonist at the 5-HT
The PI3K is activated by G protein-coupled receptors and tyrosine kinase receptors.
has been investigated for its effect on AMPA receptors and researched for potential use in the trea
ocriptine is a potent agonist at dopamine D2 receptors and various serotonin receptors.
It binds to all known somatostatin receptors, and shares many pharmacological and functio
Steroid hormone receptors and related receptors are generally soluble
mones at Chicago, where he isolated estrogen receptors and discovered their importance in breast ca
2-AG can also activate both cannabinoid receptors and is inactivated by monoacylglycerol lipas
dy produces antibodies against acetylcholine receptors, and thus inhibits signal transmission acros
lacks any significant affinity for adenosine receptors and does not produce stimulant effects.
eficiency is a defect in the body's cytokine receptors and their signaling.
ese include the Toll family of innate immune receptors and the receptor for IL-18.
benzodiazepines, lacking affinity for GABAA receptors and instead acting as a cholecystokinin anta
Various Eph receptors and ephrins are expressed in these regions,
neurotransmitters which interact with nerve receptors and smooth muscle cells.
rongest actions are at the 5-HT2B and 5-HT2C receptors and its discriminative cue is mediated prima
ving amongst others an interaction between δ receptors and mitochondrial K(ATP) channels.
The venom blocks octopamine receptors and the cockroach fails to show normal escap
antagonist action at nicotinic acetylcholine receptors, and it has also been shown to reduce the co
The diverse feature of the chemotaxis receptors and ligands provides the possibility to sele
binds to the glucocorticoid and progesterone receptors and therefore blocks the activity of the end
It stimulates dopaminergic and serotonergic receptors and blocks alpha-adrenoreceptors.
e derived from A domains of various membrane receptors and have a rigid structure, stabilised by di
s down-regulation of Ca2+ -impermeable GluR2 receptors and inhibits calpain, a Ca2+ -activated prot
macromolecular systems such as ion channels, receptors, and protein kinases.
nded research consortium focussed on nuclear receptors and nuclear receptor coregulators.
s is the influx of calcium through the NMDAR receptors and the resultant activation of Ca2+/calmodu
re mediated through muscarinic acetylcholine receptors and can be prevented by prior administration
ce, Senomyx has identified hundreds of taste receptors and currently owns 113 patents on their disc
e, but it does not act at the classic opioid receptors and its actions are not antagonized by the o
of a variety of ion channels, including NMDA receptors and AMPA receptors.
This can bind to Interleukin-2 receptors and introduce the diphtheria toxin into cell
ergic, adrenergic, muscarinic or cannabinoid receptors and does not block potassium or calcium curr
ulation, molecular endocrinology and steroid receptors and transcriptional coactivators.
lso partial agonist of µ-opioid and δ-opioid receptors, and competitive antagonist of ϰ-opioid rece
ist with high affinity to the D2, D3, and D4 receptors, and with moderate affinity for the 5-HT2 re
negligible affinity for the 5-HT1A or 5-HT2C receptors, and over 400-fold lower affinity for the D2
0 mg/day due to its ability to antagonise H3 receptors and thus increase the release of serotonin a
ule that interacts with various cell surface receptors and mediates cell apoptotic signals.
Title: Interactions of Eph-related receptors and ligands confer rostrocaudal pattern to t
a selective radioligand for the cannabinoid receptors and has been used as its 131I derivative for
It is a partial agonist of benzodiazepine receptors and has been shown to possess both anxiolyti
st likely caused by activity at kappa opioid receptors and sigma receptors.
It belongs to the type I cytokine receptors, and has been shown to form a heterodimeric
gonist-antagonist at nicotinic acetylcholine receptors and an antagonist at μ-opioid receptors.
-Bungarotoxin blocks nicotinic acetylcholine receptors and has been used to isolate and study them;
localizes with intracellular adrenal steroid receptors and converts cortisol (an active mineralcort
HT2C), 5-HT6, 5-HT7, α1-adrenergic, and NMDA receptors, and as agonists at the sigma receptors (σ1
it possesses intrinsic activity at the D2/D3 receptors, and acts as a weak partial agonist at these
modes of action such as through histamine H3 receptors and glutamate.
s, including stimulation of alpha and beta-1 receptors and inhibition of noradrenaline and tyramine
various experiments to sever Westlake's pain receptors and enhance his strength to superhuman level
eraction with G-protein-coupled somatostatin receptors and inhibition of the release of numerous se
Palifermin binds to epithelial cell-surface receptors and stimulates epithelial cell proliferation
bitter taste work through G protein-coupled receptors, and the savory sensation is activated by gl
s as a positive allosteric modulator of AMPA receptors, and has nootropic effects in animal studies
y over the closely related 5-HT2A and 5-HT2C receptors and other receptor targets.
s act through intracellular (mostly nuclear) receptors and, thus, are considered to be intracrines.
ts also commonly have action at α-adrenergic receptors and/or 5-HT receptors.
The C-terminus of CB2 receptors appears to play a critical role in the regul
The M2 muscarinic receptors are located in the heart, where they act to
Typically type II cytokine receptors are hetrodimers or multimers with a high and
These receptors are related predominantly by sequence simila
Complement receptors are responsible for detecting pathogens by m
Muscarinic receptors are found in both the central nervous system
For example, 5-HT1E receptors are abundant in the hippocampus but are not
Most frizzled receptors are coupled to the beta-catenin canonical si
ding the interaction of losigamone with GABA receptors are inconsistent: it increases GABA-induced
It is now known that S1P receptors are members of the Lysophospholipid receptor
r antidepressant on various transporters and receptors are summarized below.
Chemotaxis receptors are expressed in the surface membrane with d
The CB2 receptors are found primarily on microglia(the immune
GABAB receptors are involved in behavioral actions of ethano
Cytokine receptors are receptors that bind cytokines.
Muscarinic receptors are metabotropic, and affect neurons over a
These methyl-accepting chemotaxis receptors are one of the first components in the senso
TGFβ receptors are single pass serine/threonine kinase rece
o other areas of the brain, and somatostatin receptors are expressed at many different sites in the
Imidazoline receptors are receptors for clonidine and other imidaz
The angiopoietin receptors are receptors that bind angiopoietin.
Ion channel linked receptors are cell membrane bound receptors.
CB2 receptors are also found throughout the gastrointestin
These receptors are heteromeric protein complexes with multi
The two main types of glutamate receptors are ionotropic receptors and metabotropic re
These olfactory receptors are membrane proteins of bipolar olfactory r
The ligands of these receptors are members of the TGF beta superfamily.
The asialoglycoprotein receptors are lectins which bind asialoglycoprotein, g
Several other LIR subfamily B receptors are expressed on immune cells where they bin
β3-adrenergic receptors are located in fat cells.
The type A GABA receptors are pentameric chloride channels assembled f
β2-adrenergic receptors are located mainly in the lungs, gastrointes
These receptors are found in the central and peripheral auto
Eph receptors are components of cell signalling pathways i
Peptide hormone receptors are often transmembrane proteins.
Galanin receptors are seven-transmembrane proteins shown to ac
N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate receptor
Retinoid receptors are nuclear receptors (a class of proteins)
These receptors are also closely related to the activin rece
Chemokines and their receptors are important for the migration of various c
β1-adrenergic receptors are located mainly in the heart and in the k
These receptors are all transmembrane proteins, composed of
Chemokines and their receptors are key regulators of the thymocytes migrati
most important functions of thyroid hormone receptors are regulation of metabolism and heart rate.
of its potency, because the appropriate CB1 receptors are not located in brain areas reponsible fo
Examples of such tonic receptors are pain receptors, joint capsule, and muscl
Glutamate receptors are (as mentioned above) also expressed in p
Sigma receptors are affected by cocaine, as cocaine function
The D1 and D5 receptors are members of the D1-like family of dopamin
These receptors are similar to type I cytokine receptors exc
Type I receptors are essential for signaling, and type II rec
Type I receptors are essential for signaling; and type II rec
These receptors are predominately expressed in cells of the
Expression of the receptors are correlated with insulin levels, as well
Examples of orphan receptors are found in the G protein-coupled receptor
V1 receptors are found in various sites around the body.
alpha7-containing receptors are known to improve prepulse inhibition, pr
G protein-coupled receptors are composed of seven membrane-spanning alph
Most older compounds acting on adenosine receptors are nonselective, with the endogenous agonis
The three receptors are dominated by three rhodopsin-like pigmen
ked to the D3 activity of pramipexole, as D3 receptors are heavily expressed in brain regions invol
Pulmonary stretch receptors are mechanoreceptors found in the lungs.
Type II receptors are considered to be constitutively active k
Signalling outputs from these receptors are influenced both by the binding of the ch
tagonists (BQ-788) which affect endothelin B receptors are used in research but have not yet reache
The LDL receptors are minimally functional, if at all.
Ion-channel-linked receptors are also called ligand-gated channels.
Soluble cytokine receptors are extremely common regulators of cytokine
Glucagon receptors are mainly expressed in liver and in kidney
5HT-3 receptors are responsible for causing many things from
Since the antigen receptors are typically composed of two variable domai
Merkel receptors are also located in the mammary glands.
Most enzyme-linked receptors are of this type.
e most active areas of search for ligands to receptors, are in the field of brain receptors.
The ligands for these receptors are free fatty acids (FFAs) and eicosanoids.
Upon activation, "low-affinity" IL-2 receptors are replaced by "high-affinity" IL-2 recepto
netic tree showing how a number of monoamine receptors are related to each other.
Some tonic receptors are permanently active and indicate a backgr
However since GABAС receptors are closely related in sequence, structure,
Neurotrophin ligands of Trk receptors are processed ligands, meaning that they are
ErbB receptors are made up of an extracellular region or ec
Metabotropic receptors are G-protein coupled receptors that mediate
that the differences between GABAС and GABAA receptors are large enough to justify maintaining the

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