「selectivity」の共起表現(1語右で並び替え)

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「selectivity」の共起表現一覧(1語右で並び替え)

selectivity

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-HT1A receptor agonist with some functional selectivity, acting as a full agonist at presynaptic an
This selectivity allows some parts of the object being heate
are added to the electrodes to enhance the selectivity and stability.
difficult to prepare, but offer much better selectivity and strength of binding than other complexa
ignant tissue and this is the basis for its selectivity and pharmacokinetic properties.
oduces two products which differ in peptide selectivity and level of restoration of surface express
ods are more expensive, thus encourage more selectivity and additional consideration.
ecular systems and mechanisms for dynamical selectivity and specificity".
rat recombinant systems, showing functional selectivity and stimulating one type of G-protein coupl
le and organic concentration, and pH on the selectivity and resolution of seven barbiturates.
yl group, generally confers significant CB2 selectivity, but reasonable CB1 affinity and selectivit
ion was found to retain 5-HT2A affinity and selectivity, but reversed activity from an antagonist t
ysts is not only detrimental to the product selectivity, but also presents a challenge for the reac
It displays functional selectivity by strongly activating 5-HT1A receptors in
properties including pore conductance, size selectivity, charge selectivity, voltage gating, and ch
n particular limitations, such as with true selectivity, clogging and, more undetectably, they prov
A selectivity coefficient is defined as the ratio of the
In ion-exchange chromatography the selectivity coefficient is defined in a slightly differ
Due to its selectivity, DOM is often used in scientific research w
s often suffers from reduced reactivity and selectivity due to the fact that the catalytic active c
low sequence conservation, which determines selectivity during protein-protein interactions (Bolano
not to evolution but rather to hydrodynamic selectivity, ecologic habitats, and differential mobili
ξ is the selectivity factor
he combination of the ripple factor and the selectivity factor specify the stopband ripple.
other subunits, and together they form the selectivity filter region of the channel pore.
rapping introduces a new binding mode and a selectivity filter to broaden the universe of molecular
The pore of sodium channels contains a selectivity filter made of negatively charged amino aci
in all potassium ion channels and forms the selectivity filter that enables the channel to transpor
A K+ channel pore domain (S5, selectivity filter, and S6).
pore, including the fundamental ideas of a selectivity filter, a wider inner vestibule and a gate
SCH-23,390 - 100-fold selectivity for D1 over D5
de is a dopamine antagonist with reasonable selectivity for the D3 subtype (9.6 times selectivity f
a sigma receptor antagonist, with moderate selectivity for the σ1 subtype.
lity at X can increase both the potency and selectivity for H1-receptors
It has approximately 10-fold selectivity for D1 and D5 over the D2 receptor.
High product selectivity for formate and formic acid (up to 90%)
ntanil is a fentanyl derivative with strong selectivity for the μ opioid receptor.
ds are known, almost all of which have high selectivity for CB2.
In rat neurons, less selectivity for kurtoxin on calcium channels is found.
the mu and delta opioid receptors, showing selectivity for the delta receptor.
ve, with its 2-methyl derivative having 40x selectivity for CB2.
eptor antagonist with approximately 10-fold selectivity for the former site over the latter.
d epinephrine, with a significantly greater selectivity for serotonin.
sion and orthostatic hypotension due to its selectivity for α1a-adrenergic receptors.
nicotinic acetylcholine receptors with high selectivity for the α4β2 subtype.
mains in that they show wide range of lipid selectivity for the major components of cell membranes,
It has a much higher selectivity for δ opioid receptors than μ receptors, an
n agonist at both CB1 and CB2 with moderate selectivity for CB1, with a Ki of 22.3nM at CB1 and 58.
It is not known whether this selectivity for the M3 receptor translates into any cli
holecystokinin antagonist, with fairly high selectivity for the CCKA subtype.
t agonist at both CB1 and CB2 with moderate selectivity for CB1, with a Ki of 0.4nM at CB1 vs 1.9nM
ro substitution instead confers significant selectivity for CB2.
isoform of 5α-redcutase, with about 15-fold selectivity for it over type I isoform of the enzyme.
tone-deaf, while crickets and mantids show selectivity for sound frequency.
SKF-83,959 - 7-fold selectivity for D1 over D5 with negligible affinity for
Lastly AH-1058 displays a greater selectivity for cardiac tissue over verapamil and ateno
-40503 is a SARM that shows good functional selectivity for bone tissue, and has relatively little
tylcholine receptor agonist with reasonable selectivity for the M1 and M4 subtypes, though it is al
rexin receptor subtype OX1, with around 70x selectivity for OX1 over OX2 receptors, and improved or
he CB1 and CB2 receptors, but with moderate selectivity for CB2, having a Ki of 5.44nM at CB2 vs 20
to the related FID detector which lacks the selectivity for nitrogen and phosphorus.
s as a cannabinoid agonist with about 1.75x selectivity for CB2 with a Ki of 90nM ± 17 and 159nM ±
3-carboxylic acid core structure, with 190x selectivity for CB2 over the related CB1 receptor.
It displays high selectivity for MAGL over other brain serine hydrolases
serotonin receptor subtypes, with moderate selectivity for 5-HT2C, but relatively low affinity for
to the dopamine transporter with increased selectivity for the norepinephrine transporters.
amine transporters although still with some selectivity for the dopamine transporter.
ound that eotaxin-1 (CCL11) has high degree selectivity for its receptor, such that they are inacti
The channels vary in selectivity for the permeating ions from nonselective b
acts as a cannabinoid agonist with about 5x selectivity for CB1 with a Ki of 29nM and 146nM at CB2.
at the CB1 receptor, giving it around 180x selectivity for CB2.
However despite this relatively high selectivity for CB2, its CB1 affinity is still too high
ts as a cannabinoid agonist with about 2.4x selectivity for CB1 with a Ki of 8.4nM ± 1.8 and 20nM ±
rexin receptor subtype OX1, with around 50x selectivity for OX1 over OX2 receptors.
ies of ionotropic glutamate receptors, with selectivity for the GluR5 subtype of the kainate recept
rboxamide at 2β, RTI-229 has extremely high selectivity for the dopamine transporter (2600x and 460
tives have been developed with much greater selectivity for butyrylcholinesterase, and both cymseri
frequencies of 9 MHz or 10.7 MHz to provide selectivity in communications receivers, or at higher f
ters tend to be used at 10.7 MHz to provide selectivity in broadcast FM receivers, or at a lower fr
Due to its selectivity in blocking the beta1 receptors in the hear
cey" feeling, which were attributed to poor selectivity in vivo over the hallucinogenic 5-HT2A rece
en the carbene is stabilized by a metal the selectivity increases.
However, the degree of size selectivity is restricted by the hiding effect describe
Selectivity is achieved at mildly basic solutions (pH 7
This lack of receptor selectivity is the basis of the poor tolerability profi
expression systems and therefore functional selectivity is not just an epiphenomenon of one particu
uninfected cells, however the mechanism of selectivity is not known.
n similar reaction, however, with increased selectivity: it allows the synthesis of asymmetric bis
a venous dosing, and acyclovir has a higher selectivity, lower inhibitory concentration and higher
ke transporter, with its extremely high DAT selectivity making it useful for distinguishing between
Therefore greater GPCR selectivity may be obtained by targeting allosteric sit
st, though based on its effects profile its selectivity may be considered controversial.
The selectivity of penciclovir may be attributed to two fac
The selectivity of the hydrozirconation of alkynes has been
ective for the CB2 receptor subtype, with a selectivity of over 5000x for CB2 vs CB1.
It improves the selectivity of lithiation reactions by breaking up the
Further improvements can be made to the selectivity of MEKC by adding chiral selectors or chira
0.00035nM) and a selectivity of over 60,000x for CB1 over CB2.. Independ
rbon tail needs to be short to maximize the selectivity of the desired mineral and the headgroup di
By existing in proximity, the speed and selectivity of binding interactions between enzymatic c
The selectivity of undergraduate institution is also a pred
difference is important for maintaining the selectivity of valinomycin for the transport of potassi
s noted as the best detergent for improving selectivity of immunoprecipitation of phosphotyrosine m
que is used mainly to enhance retention and selectivity of various solutes that would otherwise be
ng affinity at CB1, explaining the high CB2 selectivity of AM-1221.
retention of an analyte and can change the selectivity of certain analytes.
eptor subtype OX2, with an IC50 of 40nM and selectivity of around 250x for OX2 over OX1 receptors.
This domain is responsible for the selectivity of the protein and consists of two subdomai
2 receptor agonist, with a Ki of 13.0nM and selectivity of around 220x for CB2 over CB1 receptors.
es it useful for distinguishing the subtype selectivity of drugs acting at the δ receptors.
ty is reduced much more, resulting in a CB1 selectivity of around 13x.
e in catalytic activity (up to 90-fold) and selectivity of a gas exposed electrode on a solid elect
with random dot stimuli to study disparity selectivity of neurons since the lateral distance requi
ist for the serotonin receptor 5-HT5A, with selectivity of around 100x over other serotonin recepto
d that the regioselectivity and atropisomer selectivity of these probable one-electron coupling rea
and selective 5-HT3 partial agonist, 1000x selectivity over other serotonin receptors
high affinity and efficacy at A2B, but poor selectivity over other adenosine receptor subtypes
ceptor agonist, with an EC50 of 1nM and 15x selectivity over 5-HT2A, although it only has moderate
at the serotonin 5-HT2B receptor, with good selectivity over the related 5-HT2A and 5-HT2C receptor
in receptor subtype 5-HT1D, with around 60x selectivity over other related receptors.
st for the adenosine A3 receptor, with high selectivity over the other three adenosine receptor sub
T2B / 5-HT2C agonist, and while it has good selectivity over 5-HT2A and other serotonin receptor su
-HT7 serotonin receptor subtypes, with good selectivity over other receptors.
r agonist, with approximately 150x and 200x selectivity over the closely related 5-HT1D and 5-HT1A
e receptor like-1) receptor, with over 100x selectivity over other opioid receptors.
erotonin 5-HT2B receptor, with around 1000x selectivity over the closely related 5-HT2A and 5-HT2C
B and 5-HT2C serotonin receptors, with good selectivity over other serotonin receptor subtypes and
st at the related D3 subtype, but with good selectivity over D4 and other unrelated receptors.
tor Y5, with a Ki of 1.5nM and around 3300x selectivity over the related Y1, Y2 and Y4 receptors.
r more selective for 5-HT1A with over 1000x selectivity over other serotonin receptor subtypes and
HT2C serotonin receptor subtypes, with good selectivity over the closely related 5-HT2A subtype, an
tor CB1, with a Ki of 0.08nM at CB1 and 18x selectivity over the related CB2 receptor.
ist for the 5-HT1A receptor and retains the selectivity over the 5-HT2A/2C receptors.
r 5-HT2A, with a Ki of 2.0 nM, and moderate selectivity over the related 5-HT2B and 5-HT2C receptor
tor agonist, with approximately 25x and 40x selectivity over the closely related 5-HT1D and 5-HT1A
ptor CB2, with a Ki of 3.4nM at CB2 and 80x selectivity over the related CB1 receptor.
urther development on the basis of its high selectivity over related receptors, ease of synthesis,
2B binding affinity (Ki) of 3.4nM, and high selectivity over the closely related 5-HT2A and 5-HT2C
serotonin 5-HT2C receptor, with around 100x selectivity over the closely related 5-HT2A and 5-HT2B
ure, possibility of large-scale production, selectivity, performance under extreme conditions and p
Functional selectivity posits that a ligand may inherently produce
e most peptide compounds, had problems with selectivity, potency, solubility and bioavailability.
According to the 2011 college selectivity ranking by U.S. News & World Report, which
to track the RF and LO stages; the onerous selectivity requirements are confined to the IF amplifi
Because of their reversibility and selectivity, RIMAs are safer than the older monoamine o
High selectivity semipermeable membranes, permeable for carb
sor (which are typical of many sensors) are selectivity, sensitivity, stability, reproducibility, r
The selectivity sequence, SVGFG, is very similar to that co
contains a number of compounds with varying selectivity, several of which are either already in cli
in layers introduce defects that may affect selectivity, so system design usually trades off the de
This gives AM-4030 a greater degree of selectivity, so while it is still a potent agonist at b
Another type of pharmacological selectivity that is unique to allosteric modulators is
Owing to this selectivity, the reagent is ideal for reductive aminati
If the two solvents show different selectivity, then the spots may be spread over the enti
one type of separation provides sufficient selectivity, there are many analytical situations where
self an essential specificity factor in ion selectivity, though that does not exclude it being part
lective D1 agonist with similar potency and selectivity to SKF 89,145.
t binds as an agonist with high potency and selectivity to mu Opioid receptors.
It is known to have a higher selectivity to etch highly p-doped silicon than the mor
s actually show a very similar SERT/DAT/NET selectivity to cocaine, although in vivo they behave di
e it has a high level of safety and a great selectivity to act on the bulbar centre of cough.
These show some selectivity towards IGF-1R over IR.
D2 dopamine receptor antagonist, with high selectivity towards D3 receptors.
ial ligands for radioisotope delivery, with selectivity towards hypoxic tissues, particularly in th
rapy, observing that their cytotoxicity and selectivity towards cancer cell is higher than that of
grees Celsius providing enhanced control in selectivity was introduced.
The molecular basis of ionic selectivity were are also identified in the transmembra
The key word for organic synthesis is selectivity, which is necessary to obtain a high yield
f the alkyl groups are the major factors in selectivity with these reagents.
the androgen receptor, producing functional selectivity with effective dissociation of anabolic and
ticism given that the present time requires selectivity with respect to topics and phrases.
roceeds with exceptional regio- and stereo- selectivity, yielding only the Markovnikov alcohol.