human | 遺伝子名 | catechol-O-methyltransferase |
同義語(エイリアス) | Catechol O-methyltransferase; COMT | |
SWISS-PROTのID | SWISS-PROT:P21964 | |
EntrezGeneのID | EntrezGene:1312 | |
その他のDBのID | HGNC:2228 |
mouse | 遺伝子名 | catechol-O-methyltransferase |
同義語(エイリアス) | D16Wsu103e; Catechol O-methyltransferase; D330014B15Rik; Comt | |
SWISS-PROTのID | SWISS-PROT:O88587 | |
EntrezGeneのID | EntrezGene:12846 | |
その他のDBのID | MGI:88470 |
rat | 遺伝子名 | catechol-O-methyltransferase |
同義語(エイリアス) | Catechol O-methyltransferase; 10375; 10377; Comt; catecholamine-O-methyltransferase; 10376 | |
SWISS-PROTのID | SWISS-PROT:P22734 | |
EntrezGeneのID | EntrezGene:24267 | |
その他のDBのID | RGD:2379 |
本文中に表示されているデータベースの説明
出典:Wikipedia
出典:『Wikipedia』 (2011/05/26 13:06 UTC 版)
Catechol-O-methyltransferase (COMT; EC 2.1.1.6) is one of several enzymes that degrade catecholamines such as dopamine, epinephrine, and norepinephrine. In humans, catechol-O-methyltransferase protein is encoded by the COMT gene. As the regulation of catecholamines is impaired in a number of medical conditions, several pharmaceutical drugs target COMT to alter its activity and therefore the availability of catecholamines. COMT was first discovered by the biochemist Julius Axelrod in 1957.