出典:Wikipedia
出典:『Wikipedia』 (2011/06/04 12:49 UTC 版)
Calcium-induced calcium release (CICR) is a process whereby calcium can trigger release of further calcium from the muscle sarcoplasmic reticulum . Originally proposed for skeletal muscle in the 1970s, subsequent research has revealed that it is even more pronounced in the cardiac muscle. It is now obvious that CICR is a widely occurring cellular signaling process present even in many non-muscle cells e.g. in the insulin secreting pancreatic beta cells and many other cells.