To provide an anti-glypican 3 antibody having higher ADCC (antibody-dependent cellular cytotoxicity) activity and CDC (complement-dependent cytotoxicity) activity compared with those of conventional antibody, and provide a cell growth inhibitor and an anticancer agent containing the antibody as an active component. 従来の抗体と比較して高いADCC(抗体依存性細胞障害)活性およびCDC(補体依存性細胞障害)活性を有する抗グリピカン3抗体、ならびにかかる抗体を有効成分とする細胞増殖抑制剤及び抗癌剤の提供。 - 特許庁