To provide a model useful for developing an antimicrobial agent for a microbial infectious disease in a living thing having an acquired immunologic mechanism, which is a model for microbial infection utilizing a living thing having only a natural immunologic mechanism. 自然免疫機構のみを有する生物を利用した微生物感染のモデルであって、獲得免疫機構を有する生物における微生物感染症の抗菌剤開発に有用なモデルを提供すること。 - 特許庁
This model mouse of immunologic disease is obtained by hybridizing a mouse to which transcription factor GATA-3 gene is transferred with a mouse to which a white albumin recognition T cell receptor gene is transferred to give a mouse to which both the genes are transferred. 転写因子GATA-3遺伝子を導入したマウスと卵白アルブミン認識T細胞レセプター遺伝子導入マウスを交配して両遺伝子を導入することからなる免疫疾患モデルマウス - 特許庁