NEW ASSAY METHOD OF SUBSTANCE FOR CONTROLLING MIGRATION OUTSIDE OF REV PROTEIN KERNEL Rev蛋白核外移行制御物質の新規アッセイ法 - 特許庁
To provide a new assay method of a substance for controlling migration outside of an Rev protein kernel. Rev蛋白核外移行制御物質の新規アッセイ法を提供すること。 - 特許庁
In this case, a cell sample having an inhibition rate of 0% and that having an inhibition rate of 100% are used contrastively, and both of them are compared, thus quantitatively evaluating the inhibition activity of migration outside of the Rev kernel of the substance to be inspected. その際、阻害率0%の細胞試料および阻害率100%の細胞試料を対照に使用して、両者との比較により被検物質のRev核外移行阻害活性を定量的に評価する。 - 特許庁
A DNA originating from HIV is transfected to a cell, and the quantity of a structural protein p24 that manifests itself as a result is determined by an ELISA method, thus evaluating the inhibition activity of migration outside of a Rev kernel in a substance to be inspected. HIV由来DNAを細胞にトランスフェクションさせ、その結果として発現する構成タンパク質p24をELISA法により定量することで、被検物質のRev核外移行阻害活性を評価する。 - 特許庁