出典:Wikipedia
出典:『Wikipedia』 (2011/06/12 18:38 UTC 版)
The calicheamicins are a class of enediyne antibiotics derived from the bacterium Micromonospora echinospora, with calicheamicin γ1 being the most notable. It was isolated originally from a rock collected by a Scripps Research Institute chemist while hiking in Waco, Texas. It is extremely toxic to all cells and its analogues have been used as targeted therapy against cancer. Calicheamicin γ1 and the related enediyne esperamicin are the two most potent antitumor agents known.