英和和英

出典:『Wikipedia』 (2011/04/25 06:53 UTC 版)

英語による解説

引用

F15845 (3-(R)-[3-(2-methoxyphenylthio-2-(S)-methylpropyl]amino-3,4-dihydro-2H-1,5 benzoxathiepine bromhydrate) is a cardiac drug proposed to have beneficial effects for the treatment of angina pectoris, arrhythmias and ischemia by inhibiting the persistent sodium current (Vacher et al., 2009; Pignier et al., 2010). The drug, currently in phase II of clinical trials, targets the persistent sodium current with selectivity and produces minimal adverse effects in current experimental studies (Vacher et al., 2009; Létienne et al. 2009; Vie et al. 2009; Pignier et al. 2010).