出典:Wikipedia
出典:『Wikipedia』 (2011/02/04 00:10 UTC 版)
Trioxifene (LY-133,314) is a selective estrogen receptor modulator (SERM) with competitive binding activity against estradiol for estrogen receptor {alpha} (ER{alpha}) and antagonistic activity against ER{alpha}-mediated gene expression. It has demonstrated anticancer effects in animal studies, indicating that it may be useful for the treatment of breast cancer.