出典:Wiktionary
出典:Wikipedia
出典:『Wikipedia』 (2011/04/05 22:30 UTC 版)
Exon shuffling is a theory, introduced by Walter Gilbert in 1977, in which different exons either within a gene or between two nonallelic genes are occasionally mixed. Gilbert suggested that exons might each encode a single protein domain, establishing a kind of modular property. In this fashion, it would be possible for exons to essentially be "mixed and matched" to produce a variety of different proteins, yielded from different combinations of such exons and their resulting domain combinations.