英和和英

名詞

oncometabolite (複数形 oncometabolites)

1. (biochemistry, pathology) Any metabolite that is associated with a cancer
   • 2015 July 11, “Mutant IDH1 Dysregulates the Differentiation of Mesenchymal Stem Cells in Association with Gene-Specific Histone Modifications to Cartilage- and Bone-Related Genes”^[1], PLOS ONE, DOI:10.1371/journal.pone.0131998: 

     Due to this pleiotropic function for dysregulating biological events, 2-HG is regarded as an oncometabolite that exerts tumor-inducing actions, and searches for IDH gene mutations have been performed in various types of malignancies [1 ,2 ].