英和和英

名詞

pseudopalisade ‎(複数形 pseudopalisades)

1. (cytology) A hypercellular zone that typically surrounds necrotic tissue
   • 2016, “Mathematical Modelling of a Brain Tumour Initiation and Early Development: A Coupled Model of Glioblastoma Growth, Pre-Existing Vessel Co-Option, Angiogenesis and Blood Perfusion”, in PLOS ONE^[1], DOI:10.1371/journal.pone.0150296:

     They proposed two potential mechanisms of pseudopalisade formation: (a) tumour cells at greatest distance from arterial supplies become hypoxic due to increased metabolic demands, leaving a central necrotic core; (b) microvascular occlusion or collapse within the neoplasm could lead to perivascular hypoxia.