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Weblio 辞書 > 英和辞典・和英辞典 > INHIBITORSの意味・解説 > INHIBITORSに関連した共起表現

「INHIBITORS」の共起表現一覧(1語右で並び替え)

該当件数 : 319



MAO), which is a target of monoamine oxidase inhibitors, a class of antidepressants.
adol also function as noradrenaline reuptake inhibitors, a property that contributes to their overal
nown to act as selective monoamine oxidase A inhibitors, a side effect which can lead to lethal sero
Sheddase inhibitors active on ADAM10 and ADAM17 can potentiate a
Chitin synthesis inhibitors affect insects for longer periods of time th
ALS Inhibitors affect grasses and dicots by inhibiting the
has led to the synthesis of highly specific inhibitors against a number of protein kinases, includi
Some haemophiliacs develop antibodies ( inhibitors) against the replacement factors given to th
These inhibitors also inhibit PDK1 explaining the higher inhi
The use of inhibitors also decreases the localized zones of high p
alled specialty pharmaceuticals (such as TNF Inhibitors) also use coupons as a marketing tactic.
ding conformation changes in serine protease inhibitors, also known as serpins, mutations of which a
With these inhibitors, an insect grows normally until it molts.
They are broad spectrum inhibitors and are chemically diverse with different ty
is a member of the serpin family of protease inhibitors, and participates in DNA and chromatin conde
s an adjunct to conventional treatments (ACE inhibitors and diuretics).
breast cancer (in combination with aromatase inhibitors) and for metastatic lung cancer (in combinat
hography and process engraving; in corrosion inhibitors; and in pharmaceutical preparations.
Proton Pump Inhibitors and C-Difficile
The effect of diuretics, ACE inhibitors and angiotensin II receptor antagonists can
es, best known of which is azoxystrobin; QoI inhibitors) and as anti-malaria agents (atovaquone).
strong serine/threonine protein phosphatase inhibitors and based on this property, calyculins might
Other ingredients include corrosion inhibitors and flow conditioners.
viruses that are resistant to other protease inhibitors and it recommended for patients who are resi
The fluoroquinolones are known as GABA inhibitors and as such have the ability to bind to neur
ste management, biologically active protease inhibitors, and chemically inert redox shuttles for dye
ilar in concept to the use of selective MAOA inhibitors and selective MAOB inhibitors in augmentatio
side the brain, to form two selective enzyme inhibitors and blocking both types of the zinc-metallop
clude peroxidase, acid phosphatase, protease inhibitors, and calcium.
The class I bacteriocins are small peptide inhibitors and include nisin and other lantibiotics.
emely toxic at low levels, both are Na+ pump inhibitors and both have nearly identical binding const
tituted phenyltropanes are highly potent MAT inhibitors and also have a very long half-life, spannin
for screening transporter substrates and/or inhibitors; and also to determine in vitro drug resista
diet and various medications especially ACE inhibitors and angiotensin receptor blockers can lower
nidate both in efficacy as dopamine reuptake inhibitors and in animal drug discrimination assays.
letal toxicity in the case of broad spectrum inhibitors) and failure to show expected results (in th
blishes new knowledge and findings on enzyme inhibitors and inhibitory processes as well as agonist/
ese drugs are known as reverse transcriptase inhibitors and include the nucleoside and nucleotide an
blood pressure (antihypertensive drugs): ACE inhibitors, angiotensin receptor blockers, α blockers,
Some JAK2 inhibitors are under development for the treatment of p
Trypsin inhibitors are chemicals that reduce the availability o
If anodic inhibitors are used at too low concentration, they can
Some corrosion inhibitors are hexamine, benzotriazole, phenylenediamin
ed levels of this enzymatic activity, though inhibitors are in development and clinical trials.
Kinase inhibitors are low molecular weight molecules that prev
Alpha-glucosidase inhibitors are used to establish greater glycemic contr
Many serpins (serine protease inhibitors) are metastable, and undergo a conformationa
COMT inhibitors are used in the treatment of Parkinson's dis
Some IGR-1R inhibitors are in various stages of development (based
Thromboxane synthase inhibitors are used as antiplatelet drugs.
RORγt inhibitors are under development for autoimmune disease
Many HDAC inhibitors are potential treatments for cancer through
Some glycosyltransferase inhibitors are of use as drugs or antibiotics.
g on September 4, 2008, that patients on TNF inhibitors are at increased risk of opportunistic funga
Some P2Y12 inhibitors are used clinically as effective inhibitors
Alpha-glucosidase inhibitors are saccharides that act as competitive inhi
Other substitutents of these inhibitors are usually designed to interact with variou
Several prolyl endopeptidase inhibitors are known, and have been suggested as possib
Pyrimidine synthesis inhibitors are used in active moderate to severe rheuma
Along with carbidopa, other DDC inhibitors are benserazide (Ro-4-4602), difluromethyldo
Xanthine oxidase inhibitors are being investigated for management of rep
Xanthine oxidase inhibitors are of two kinds: purine analogues and other
Allosteric serotonin reuptake inhibitors are therefore not a therapeutically distinct
A large number of AChE inhibitors are used in both medicine and agriculture.
Integrase inhibitors are a class of antiretroviral drug designed
ve bacteria, and synthetic versions of these inhibitors are in clinical trials for the prevention of
Early results from clinical trials of PARP inhibitors are considered to be important and promising
Thus, while ACE inhibitors are still considered first-line therapy in h
For this reason, several FTase inhibitors are undergoing testing as anti-cancer agents
ly SNRIs (serotonin-norepinephrine re-uptake inhibitors), as this increases the risk of the above sy
More recently a new series of renin inhibitors based on the ketopiperazine structure was de
Two angiogenesis inhibitors based on Dr. Folkman's hypothesis and develo
of nucleoside analogue reverse transcriptase inhibitors, because DNA production by reverse transcrip
Both inhibitors bind with high affinity and specificity, and
Most TCAs act as reuptake inhibitors, but opipramol does not, and instead acts as
does not produce nearly as many fermentation inhibitors but must be separated from the sugar stream
ltramadol are inactive as serotonin reuptake inhibitors, but (-)-O-desmethyltramadol retains activit
hibited by hirudin and other direct thrombin inhibitors, but not by heparin.
go a chemical reaction and can act as enzyme inhibitors by blocking their active site.
While Novartis was developing inhibitors by modification of the peptide-like inhibito
tose intolerance or the use of α-glucosidase inhibitors by diabetics), gluten (protein in wheat, bar
raig Jordan and initial studies of aromatase inhibitors by 2005 Kettering prize recipient Angela Bro
OPS online database for peptidases and their inhibitors: C01.032
After some time, though, some inhibitors can develop a permanent bond with cholineste
Therapeutic ADAM inhibitors can potentiate anti-cancer therapy.
Angiotensin-converting enzyme (ACE) inhibitors can also be used.
s, particularly injectable drugs such as TNF inhibitors can be worth several thousands of dollars pe
Chitin synthesis inhibitors can also kill eggs by disrupting normal embr
Inhibitors can escape removal during the DNA purificati
Protease inhibitors changed the very nature of the AIDS epidemic
r (sedative which contains monoamine oxidase inhibitors), Citrus aurantium (contains small amounts o
f resins, waxes, nylons, plastics, corrosion inhibitors, coatings, lubricating greases and cosmetics
Although aromatase inhibitors could be considered antiestrogens by some de
with the older non-selective cholinesterase inhibitors currently used for this application, such as
Specific inhibitors developed using rational design have recentl
Conventional protease inhibitors do not completely inactivate Factor I but th
he Cybermen by shutting down their emotional inhibitors, enabling them to "see" what had become of t
devoted to the development of protein kinase inhibitors, especially tyrphostins/TKIs.
by the use of diuretics, beta blockers, ACE inhibitors, etc., or to repair/replace the mitral valve
tanning leather, antiperspirants, corrosion inhibitors, extraction of uranium, petroleum refining,
ated that he had studied proteases and their inhibitors for twenty years.
been conducted on everolimus and other mTOR inhibitors for use in a number of cancers.
, A. The Potential Role of Serine Proteinase Inhibitors for the Prevention of Plaque Rupture.
There are three classes of commonly used inhibitors for metalloproteinases.
caution should be used when prescribing PDE5 inhibitors for erectile dysfunction for patients receiv
semide) and UV-absorber as well as corrosion inhibitors for metals and mold inhibitors in soya sauce
They have also been used as specific inhibitors for various enzymes.
ug have been developed as CYP2C9 and CYP2C19 inhibitors for use in research.
As well as methods for the removal of inhibitors from samples before PCR, some DNA polymerase
It also contains a group of proteinase inhibitors from the plants Arabidopsis thaliana and Bra
Synthetic inhibitors generally contain a chelating group which bi
e solution in the presence of polymerization inhibitors gives crude chloroprene.
A number of rationally designed MMP inhibitors have shown some promise in the treatment of
nger popular as many orally active aromatase inhibitors have been identified.
Some Akt inhibitors have undergone clinical trials.
ct primarily as selective serotonin reuptake inhibitors have also been found to increase the levels
Zinc finger inhibitors have been tested for their efficacy in treat
terference that selective serotonin reuptake inhibitors have on serotonergic psychedelic drugs.
seeds and various serine proteases and their inhibitors have been determined by his group.
FTase inhibitors have shown efficacy as anti-parasitic agents
Competitive inhibitors have the same y-intercept as uninhibited enz
Acetylcholinesterase inhibitors, highly toxic to other animals and humans, a
OPS online database for peptidases and their inhibitors: I04.001
OPS online database for peptidases and their inhibitors: I04.033
Beta-lactamase inhibitors in clinical use include clavulanic acid and
urrently one of the furthest advanced PDE10A inhibitors in development and has progressed through to
se of atropine along with anticholinesterase inhibitors in order to prevent side effects.
blasts, suggesting a potential role for PDE7 inhibitors in the treatment of osteoporosis.
among the tropane-derived dopamine reuptake inhibitors in that the active stereoisomer is the (S) e
The global market for TNF inhibitors in 2007 was $10Bn, and in 2008 it was $13.5B
te a dissertation entitled Monoamine oxidase inhibitors in Amazonian hallucinogenic plants: ethnobot
t the NYU School of Medicine using synthesis inhibitors in psychiatric patients responding to antide
Exogenous matrix metalloproteinase inhibitors include batimastat and marimastat.
COMT inhibitors include tolcapone and entacapone, which are
Other inhibitors include 2-phosphoglycolate, a transition sta
es of drugs that are transition state analog inhibitors include flu medications such as the neuramin
HMG-CoA reductase inhibitors including simvastatin, simvastatin acid, lov
omologous to the Kunitz-type serine protease inhibitors, including bovine pancreatic trypsin inhibit
Other inhibitors involved in this process are noggin and chor
argely disappointing clinical results of MMP inhibitors is unclear, especially in light of their act
The mechanism of DPP-4 inhibitors is to increase incretin levels (GLP-1 and GI
apy against bleeding; the incidence of these inhibitors is dependent of various factors, including t
ACCase Inhibitors kill grasses and inhibit the first step in l
ril was the first member of the group of ACE inhibitors known as the dicarboxylate-containing ACE in
OPS online database for peptidases and their inhibitors: LI27.001
ENTs are blocked by adenosine reuptake inhibitors like dipyridamole and dilazep, drugs used cl
ge of ACE inhibition by active site-directed inhibitors like captopril, enalapril, lisinopril, and o
nnels can still be inhibited by one of their inhibitors, like Charybdotoxin (CTX)(Kaczorowski et al.
ACE inhibitors like enalapril prevent this effect.
Dopamine β-hydroxylase (DBH) inhibitors like disulfiram (Antabuse), which is used in
Tyrosine hydroxylase (TH) inhibitors like metirosine (Demser), which is used in t
istration of Atorvastatin with one of CYP3A4 inhibitors like itraconazole, telithromycin and voricon
s is less likely to happen with other CYP3A4 inhibitors like diltiazem, erythromycin, fluconazole, k
might interact with dihydrofolate reductase inhibitors like methotrexate and trimethoprim, and NO-e
OPS online database for peptidases and their inhibitors: M10.006
OPS online database for peptidases and their inhibitors: M10.009
OPS online database for peptidases and their inhibitors: M10.013
OPS online database for peptidases and their inhibitors: M10.014
OPS online database for peptidases and their inhibitors: M10.017
OPS online database for peptidases and their inhibitors: M10.019
OPS online database for peptidases and their inhibitors: M10.051
OPS online database for peptidases and their inhibitors: M12.021
OPS online database for peptidases and their inhibitors: M12.208
OPS online database for peptidases and their inhibitors: M12.220
OPS online database for peptidases and their inhibitors: M12.222
OPS online database for peptidases and their inhibitors: M12.235
OPS online database for peptidases and their inhibitors: M18.002
dition of, or dosage change in, these CYP3A4 inhibitors makes it harder for the body to metabolize a
Exogenous angiogenesis inhibitors may be drugs or a dietary components.
Inhibitors may be present in the original sample, such
relevant to understanding how PDE5-selective inhibitors may alter signal transduction pathways in ph
PDE5-selective inhibitors may show good discrimination of PDE5 from mo
Because of the Akt[1] functions above Akt inhibitors may treat cancers such as neuroblastoma.
mTOR inhibitors may also be useful for treating several age-
OPS online database for peptidases and their inhibitors: Metallo Peptidases
HIV protease inhibitors, nefazodone, sertraline, grapefruit juice, f
tion of non-nucleoside reverse transcriptase inhibitors, notably etravirine and rilpivirine.
ajor pharmaceutical companies are developing inhibitors of the Na/glucose cotransporters to treat di
Tryptolines are also potent reuptake inhibitors of serotonin and epinephrine, with a signifi
netrating peptides that act as intracellular inhibitors of signal transference from receptors to G p
chemical compound, one of the noncompetitive inhibitors of cytochrome P450 2C9.
breast cancer, a small-molecule or antibody inhibitors of LOX abolished metastasis.
ine were synthesized that behave as combined inhibitors of monoamine uptake and nAChRs.
(S)-thiorphan are isomeric thiol-containing inhibitors of endopeptidase EC 24-11 (also called "enke
anticholinergics (benztropine), which act as inhibitors of the neurotransmitter acetylcholine, may p
iopanoic acid and ipodate sodium are potent inhibitors of thyroid hormone release from thyroid glan
role in drug-induced malformations is known: inhibitors of the last step of cholesterol biosynthesis
Reversible inhibitors of monoamine oxidase A (RIMAs) are a class o
Hydroxymates are particularly potent inhibitors of MMPs and other zinc-dependent enzymes, du
gs didanosine and zidovudine are more potent inhibitors of mitochondrial DNA synthesis than tenofovi
on and a related halogenated monoterpene are inhibitors of the enzyme DNA methyltransferase, suggest
These include INKS for inhibitors of kinase, KIPS for kinase inhibitors and CK
Inhibitors of insect alpha-amylases from sorghum.
Many inhibitors of glycosyltransferases are known.
d by a local balance between stimulators and inhibitors of new vessel growth and is suppressed under
In 2005 it was shown that inhibitors of EGFR could enhance axonal regeneration on
ed by a number of independent stimulators or inhibitors of iron absorption.
Synthetic inhibitors of the enzyme have been discovered.
The calphostins are inhibitors of protein kinase C (PKC).
The Aminocoumarin antibiotics are known inhibitors of DNA gyrase.
                                                                                                    


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