「INHIBITORS」の共起表現一覧(1語右で並び替え)
該当件数 : 319件
MAO), which is a target of monoamine oxidase | inhibitors, a class of antidepressants. |
adol also function as noradrenaline reuptake | inhibitors, a property that contributes to their overal |
nown to act as selective monoamine oxidase A | inhibitors, a side effect which can lead to lethal sero |
Sheddase | inhibitors active on ADAM10 and ADAM17 can potentiate a |
Chitin synthesis | inhibitors affect insects for longer periods of time th |
ALS | Inhibitors affect grasses and dicots by inhibiting the |
has led to the synthesis of highly specific | inhibitors against a number of protein kinases, includi |
Some haemophiliacs develop antibodies ( | inhibitors) against the replacement factors given to th |
These | inhibitors also inhibit PDK1 explaining the higher inhi |
The use of | inhibitors also decreases the localized zones of high p |
alled specialty pharmaceuticals (such as TNF | Inhibitors) also use coupons as a marketing tactic. |
ding conformation changes in serine protease | inhibitors, also known as serpins, mutations of which a |
With these | inhibitors, an insect grows normally until it molts. |
They are broad spectrum | inhibitors and are chemically diverse with different ty |
is a member of the serpin family of protease | inhibitors, and participates in DNA and chromatin conde |
s an adjunct to conventional treatments (ACE | inhibitors and diuretics). |
breast cancer (in combination with aromatase | inhibitors) and for metastatic lung cancer (in combinat |
hography and process engraving; in corrosion | inhibitors; and in pharmaceutical preparations. |
Proton Pump | Inhibitors and C-Difficile |
The effect of diuretics, ACE | inhibitors and angiotensin II receptor antagonists can |
es, best known of which is azoxystrobin; QoI | inhibitors) and as anti-malaria agents (atovaquone). |
strong serine/threonine protein phosphatase | inhibitors and based on this property, calyculins might |
Other ingredients include corrosion | inhibitors and flow conditioners. |
viruses that are resistant to other protease | inhibitors and it recommended for patients who are resi |
The fluoroquinolones are known as GABA | inhibitors and as such have the ability to bind to neur |
ste management, biologically active protease | inhibitors, and chemically inert redox shuttles for dye |
ilar in concept to the use of selective MAOA | inhibitors and selective MAOB inhibitors in augmentatio |
side the brain, to form two selective enzyme | inhibitors and blocking both types of the zinc-metallop |
clude peroxidase, acid phosphatase, protease | inhibitors, and calcium. |
The class I bacteriocins are small peptide | inhibitors and include nisin and other lantibiotics. |
emely toxic at low levels, both are Na+ pump | inhibitors and both have nearly identical binding const |
tituted phenyltropanes are highly potent MAT | inhibitors and also have a very long half-life, spannin |
for screening transporter substrates and/or | inhibitors; and also to determine in vitro drug resista |
diet and various medications especially ACE | inhibitors and angiotensin receptor blockers can lower |
nidate both in efficacy as dopamine reuptake | inhibitors and in animal drug discrimination assays. |
letal toxicity in the case of broad spectrum | inhibitors) and failure to show expected results (in th |
blishes new knowledge and findings on enzyme | inhibitors and inhibitory processes as well as agonist/ |
ese drugs are known as reverse transcriptase | inhibitors and include the nucleoside and nucleotide an |
blood pressure (antihypertensive drugs): ACE | inhibitors, angiotensin receptor blockers, α blockers, |
Some JAK2 | inhibitors are under development for the treatment of p |
Trypsin | inhibitors are chemicals that reduce the availability o |
If anodic | inhibitors are used at too low concentration, they can |
Some corrosion | inhibitors are hexamine, benzotriazole, phenylenediamin |
ed levels of this enzymatic activity, though | inhibitors are in development and clinical trials. |
Kinase | inhibitors are low molecular weight molecules that prev |
Alpha-glucosidase | inhibitors are used to establish greater glycemic contr |
Many serpins (serine protease | inhibitors) are metastable, and undergo a conformationa |
COMT | inhibitors are used in the treatment of Parkinson's dis |
Some IGR-1R | inhibitors are in various stages of development (based |
Thromboxane synthase | inhibitors are used as antiplatelet drugs. |
RORγt | inhibitors are under development for autoimmune disease |
Many HDAC | inhibitors are potential treatments for cancer through |
Some glycosyltransferase | inhibitors are of use as drugs or antibiotics. |
g on September 4, 2008, that patients on TNF | inhibitors are at increased risk of opportunistic funga |
Some P2Y12 | inhibitors are used clinically as effective inhibitors |
Alpha-glucosidase | inhibitors are saccharides that act as competitive inhi |
Other substitutents of these | inhibitors are usually designed to interact with variou |
Several prolyl endopeptidase | inhibitors are known, and have been suggested as possib |
Pyrimidine synthesis | inhibitors are used in active moderate to severe rheuma |
Along with carbidopa, other DDC | inhibitors are benserazide (Ro-4-4602), difluromethyldo |
Xanthine oxidase | inhibitors are being investigated for management of rep |
Xanthine oxidase | inhibitors are of two kinds: purine analogues and other |
Allosteric serotonin reuptake | inhibitors are therefore not a therapeutically distinct |
A large number of AChE | inhibitors are used in both medicine and agriculture. |
Integrase | inhibitors are a class of antiretroviral drug designed |
ve bacteria, and synthetic versions of these | inhibitors are in clinical trials for the prevention of |
Early results from clinical trials of PARP | inhibitors are considered to be important and promising |
Thus, while ACE | inhibitors are still considered first-line therapy in h |
For this reason, several FTase | inhibitors are undergoing testing as anti-cancer agents |
ly SNRIs (serotonin-norepinephrine re-uptake | inhibitors), as this increases the risk of the above sy |
More recently a new series of renin | inhibitors based on the ketopiperazine structure was de |
Two angiogenesis | inhibitors based on Dr. Folkman's hypothesis and develo |
of nucleoside analogue reverse transcriptase | inhibitors, because DNA production by reverse transcrip |
Both | inhibitors bind with high affinity and specificity, and |
Most TCAs act as reuptake | inhibitors, but opipramol does not, and instead acts as |
does not produce nearly as many fermentation | inhibitors but must be separated from the sugar stream |
ltramadol are inactive as serotonin reuptake | inhibitors, but (-)-O-desmethyltramadol retains activit |
hibited by hirudin and other direct thrombin | inhibitors, but not by heparin. |
go a chemical reaction and can act as enzyme | inhibitors by blocking their active site. |
While Novartis was developing | inhibitors by modification of the peptide-like inhibito |
tose intolerance or the use of α-glucosidase | inhibitors by diabetics), gluten (protein in wheat, bar |
raig Jordan and initial studies of aromatase | inhibitors by 2005 Kettering prize recipient Angela Bro |
OPS online database for peptidases and their | inhibitors: C01.032 |
After some time, though, some | inhibitors can develop a permanent bond with cholineste |
Therapeutic ADAM | inhibitors can potentiate anti-cancer therapy. |
Angiotensin-converting enzyme (ACE) | inhibitors can also be used. |
s, particularly injectable drugs such as TNF | inhibitors can be worth several thousands of dollars pe |
Chitin synthesis | inhibitors can also kill eggs by disrupting normal embr |
Inhibitors can escape removal during the DNA purificati | |
Protease | inhibitors changed the very nature of the AIDS epidemic |
r (sedative which contains monoamine oxidase | inhibitors), Citrus aurantium (contains small amounts o |
f resins, waxes, nylons, plastics, corrosion | inhibitors, coatings, lubricating greases and cosmetics |
Although aromatase | inhibitors could be considered antiestrogens by some de |
with the older non-selective cholinesterase | inhibitors currently used for this application, such as |
Specific | inhibitors developed using rational design have recentl |
Conventional protease | inhibitors do not completely inactivate Factor I but th |
he Cybermen by shutting down their emotional | inhibitors, enabling them to "see" what had become of t |
devoted to the development of protein kinase | inhibitors, especially tyrphostins/TKIs. |
by the use of diuretics, beta blockers, ACE | inhibitors, etc., or to repair/replace the mitral valve |
tanning leather, antiperspirants, corrosion | inhibitors, extraction of uranium, petroleum refining, |
ated that he had studied proteases and their | inhibitors for twenty years. |
been conducted on everolimus and other mTOR | inhibitors for use in a number of cancers. |
, A. The Potential Role of Serine Proteinase | Inhibitors for the Prevention of Plaque Rupture. |
There are three classes of commonly used | inhibitors for metalloproteinases. |
caution should be used when prescribing PDE5 | inhibitors for erectile dysfunction for patients receiv |
semide) and UV-absorber as well as corrosion | inhibitors for metals and mold inhibitors in soya sauce |
They have also been used as specific | inhibitors for various enzymes. |
ug have been developed as CYP2C9 and CYP2C19 | inhibitors for use in research. |
As well as methods for the removal of | inhibitors from samples before PCR, some DNA polymerase |
It also contains a group of proteinase | inhibitors from the plants Arabidopsis thaliana and Bra |
Synthetic | inhibitors generally contain a chelating group which bi |
e solution in the presence of polymerization | inhibitors gives crude chloroprene. |
A number of rationally designed MMP | inhibitors have shown some promise in the treatment of |
nger popular as many orally active aromatase | inhibitors have been identified. |
Some Akt | inhibitors have undergone clinical trials. |
ct primarily as selective serotonin reuptake | inhibitors have also been found to increase the levels |
Zinc finger | inhibitors have been tested for their efficacy in treat |
terference that selective serotonin reuptake | inhibitors have on serotonergic psychedelic drugs. |
seeds and various serine proteases and their | inhibitors have been determined by his group. |
FTase | inhibitors have shown efficacy as anti-parasitic agents |
Competitive | inhibitors have the same y-intercept as uninhibited enz |
Acetylcholinesterase | inhibitors, highly toxic to other animals and humans, a |
OPS online database for peptidases and their | inhibitors: I04.001 |
OPS online database for peptidases and their | inhibitors: I04.033 |
Beta-lactamase | inhibitors in clinical use include clavulanic acid and |
urrently one of the furthest advanced PDE10A | inhibitors in development and has progressed through to |
se of atropine along with anticholinesterase | inhibitors in order to prevent side effects. |
blasts, suggesting a potential role for PDE7 | inhibitors in the treatment of osteoporosis. |
among the tropane-derived dopamine reuptake | inhibitors in that the active stereoisomer is the (S) e |
The global market for TNF | inhibitors in 2007 was $10Bn, and in 2008 it was $13.5B |
te a dissertation entitled Monoamine oxidase | inhibitors in Amazonian hallucinogenic plants: ethnobot |
t the NYU School of Medicine using synthesis | inhibitors in psychiatric patients responding to antide |
Exogenous matrix metalloproteinase | inhibitors include batimastat and marimastat. |
COMT | inhibitors include tolcapone and entacapone, which are |
Other | inhibitors include 2-phosphoglycolate, a transition sta |
es of drugs that are transition state analog | inhibitors include flu medications such as the neuramin |
HMG-CoA reductase | inhibitors including simvastatin, simvastatin acid, lov |
omologous to the Kunitz-type serine protease | inhibitors, including bovine pancreatic trypsin inhibit |
Other | inhibitors involved in this process are noggin and chor |
argely disappointing clinical results of MMP | inhibitors is unclear, especially in light of their act |
The mechanism of DPP-4 | inhibitors is to increase incretin levels (GLP-1 and GI |
apy against bleeding; the incidence of these | inhibitors is dependent of various factors, including t |
ACCase | Inhibitors kill grasses and inhibit the first step in l |
ril was the first member of the group of ACE | inhibitors known as the dicarboxylate-containing ACE in |
OPS online database for peptidases and their | inhibitors: LI27.001 |
ENTs are blocked by adenosine reuptake | inhibitors like dipyridamole and dilazep, drugs used cl |
ge of ACE inhibition by active site-directed | inhibitors like captopril, enalapril, lisinopril, and o |
nnels can still be inhibited by one of their | inhibitors, like Charybdotoxin (CTX)(Kaczorowski et al. |
ACE | inhibitors like enalapril prevent this effect. |
Dopamine β-hydroxylase (DBH) | inhibitors like disulfiram (Antabuse), which is used in |
Tyrosine hydroxylase (TH) | inhibitors like metirosine (Demser), which is used in t |
istration of Atorvastatin with one of CYP3A4 | inhibitors like itraconazole, telithromycin and voricon |
s is less likely to happen with other CYP3A4 | inhibitors like diltiazem, erythromycin, fluconazole, k |
might interact with dihydrofolate reductase | inhibitors like methotrexate and trimethoprim, and NO-e |
OPS online database for peptidases and their | inhibitors: M10.006 |
OPS online database for peptidases and their | inhibitors: M10.009 |
OPS online database for peptidases and their | inhibitors: M10.013 |
OPS online database for peptidases and their | inhibitors: M10.014 |
OPS online database for peptidases and their | inhibitors: M10.017 |
OPS online database for peptidases and their | inhibitors: M10.019 |
OPS online database for peptidases and their | inhibitors: M10.051 |
OPS online database for peptidases and their | inhibitors: M12.021 |
OPS online database for peptidases and their | inhibitors: M12.208 |
OPS online database for peptidases and their | inhibitors: M12.220 |
OPS online database for peptidases and their | inhibitors: M12.222 |
OPS online database for peptidases and their | inhibitors: M12.235 |
OPS online database for peptidases and their | inhibitors: M18.002 |
dition of, or dosage change in, these CYP3A4 | inhibitors makes it harder for the body to metabolize a |
Exogenous angiogenesis | inhibitors may be drugs or a dietary components. |
Inhibitors may be present in the original sample, such | |
relevant to understanding how PDE5-selective | inhibitors may alter signal transduction pathways in ph |
PDE5-selective | inhibitors may show good discrimination of PDE5 from mo |
Because of the Akt[1] functions above Akt | inhibitors may treat cancers such as neuroblastoma. |
mTOR | inhibitors may also be useful for treating several age- |
OPS online database for peptidases and their | inhibitors: Metallo Peptidases |
HIV protease | inhibitors, nefazodone, sertraline, grapefruit juice, f |
tion of non-nucleoside reverse transcriptase | inhibitors, notably etravirine and rilpivirine. |
ajor pharmaceutical companies are developing | inhibitors of the Na/glucose cotransporters to treat di |
Tryptolines are also potent reuptake | inhibitors of serotonin and epinephrine, with a signifi |
netrating peptides that act as intracellular | inhibitors of signal transference from receptors to G p |
chemical compound, one of the noncompetitive | inhibitors of cytochrome P450 2C9. |
breast cancer, a small-molecule or antibody | inhibitors of LOX abolished metastasis. |
ine were synthesized that behave as combined | inhibitors of monoamine uptake and nAChRs. |
(S)-thiorphan are isomeric thiol-containing | inhibitors of endopeptidase EC 24-11 (also called "enke |
anticholinergics (benztropine), which act as | inhibitors of the neurotransmitter acetylcholine, may p |
iopanoic acid and ipodate sodium are potent | inhibitors of thyroid hormone release from thyroid glan |
role in drug-induced malformations is known: | inhibitors of the last step of cholesterol biosynthesis |
Reversible | inhibitors of monoamine oxidase A (RIMAs) are a class o |
Hydroxymates are particularly potent | inhibitors of MMPs and other zinc-dependent enzymes, du |
gs didanosine and zidovudine are more potent | inhibitors of mitochondrial DNA synthesis than tenofovi |
on and a related halogenated monoterpene are | inhibitors of the enzyme DNA methyltransferase, suggest |
These include INKS for | inhibitors of kinase, KIPS for kinase inhibitors and CK |
Inhibitors of insect alpha-amylases from sorghum. | |
Many | inhibitors of glycosyltransferases are known. |
d by a local balance between stimulators and | inhibitors of new vessel growth and is suppressed under |
In 2005 it was shown that | inhibitors of EGFR could enhance axonal regeneration on |
ed by a number of independent stimulators or | inhibitors of iron absorption. |
Synthetic | inhibitors of the enzyme have been discovered. |
The calphostins are | inhibitors of protein kinase C (PKC). |
The Aminocoumarin antibiotics are known | inhibitors of DNA gyrase. |
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