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Weblio 辞書 > 英和辞典・和英辞典 > Metabolitesの意味・解説 > Metabolitesに関連した共起表現

「Metabolites」の共起表現一覧(1語左で並び替え)

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Researchers theorized that abnormal metabolites of endogenous chemicals such as tryptamine,
mined the proportion of various acetanilide metabolites in human urine.
les such as bilirubin, the arachidonic acid metabolites lipoxin A4 and prostaglandin G, modified lo
matic hydrolysis to several carboxylic acid metabolites, whose urinary excretion half-lives are in
mulation of the parent drug or their active metabolites (e.g.
primary and secondary amines (called active metabolites 1 and 2) with half-lives of 14 and 16 hours
bladder, apaziquone is converted to active metabolites by intracellular reductases.
Thus premazepam produces no active metabolites in humans.
lized and may have pharmacologically active metabolites.
The active metabolites alkylate DNA and lead to apoptotic cell dea
a long duration of action due to its active metabolites.
Adinazolam was reported to have active metabolites in the August 1984 issue of The Journal of
oxazolam were tested rather than the active metabolites, this is purely speculative.
than diazepam due to its long-acting active metabolites, which contribute significantly to its effe
life and AUC of zolmitriptan and its active metabolites were approximately doubled (see CLINICAL PH
Alkylresorcinol metabolites, 3,5-dihydroxybenzoic acid (DHBA) and 3,5-d
Not only analysis of lipids but also metabolites of drugs and natural compounds from plants,
The interconversion of amide and amine metabolites of 2-AAF can further occur via the microsom
ed positive for amphetamine and amphetamine metabolites.
is is in marked contrast with the analogous metabolites of arachidonic acid (AA), which are the ser
The evidence from many genes and metabolites responsible for schizophrenia all point to
so the mix of both the parent compound and metabolites produced contributes significantly to the c
Click on genes, proteins and metabolites below to visit Gene Wiki pages and related
ee fatty acids and ketone bodies, which are metabolites produced in excess in diabetes mellitus.
Many alkaloids and other aromatic metabolites.
ne derivatives may be formed in the body as metabolites of some drugs, and this was once thought to
the metals are not typically considered as metabolites.
angement in the blood serum levels of basic metabolites.
The types of biochemicals ( metabolites) which can be studied include choline-conta
compounds, biomarker, metabolites, peptides or proteins by their molecular ma
The release of both metabolites may protect tumor cells from immune attacks
be metabolised in vivo, resulting in bound metabolites in the liver tissue, and that damage was mo
Bupropion metabolites erythro-hydrobupropion and threo-hydrobupro
n, in various experiments, to be induced by metabolites such as agmatine and lysine that would fit
matic hydrocarbons can produce carcinogenic metabolites, although there is no evidence to show that
are effectively interchangeable for certain metabolites even though the total effects of each pathw
eadily search the database and characterize metabolites through features such as accurate mass, sin
is absorbed existing as chemically-modified metabolites destined for rapid excretion.
Exposure to chlordane metabolites may be associated with testicular cancer.
tandards, and the first to develop critical metabolites, impurities, and degradants of certain drug
Vitamin D metabolites (25 (OH) D, 1, 25 (OH) 2 D) promote cellula
ikely to have high levels of [DEHP and DBP] metabolites in their urine than men without those probl
a family of decarboxylated and deiodinated metabolites of the thyroid hormones thyroxine (T4) and
roducing primarily mono- and didemethylated metabolites.
tandem MS data on more than 4,000 distinct metabolites, over 20,000 high-resolution ESI-QTOF MS/MS
B urine samples that showed traces of drug metabolites, but rather, sworn testimony from Sonye and
clude Drugs-of-Abuse, Pharmaceuticals, Drug Metabolites and Impurities, P450 metabolites, Glucuroni
od by moving substances, in this case, drug metabolites, from blood into urine.
depurination is the presence of endogenous metabolites in cell undergoing chemical reactions.
For example, high energy metabolites such as ATP and PEP are alkyl phosphates, a
level and activity of these potent estrogen metabolites.
estrogen metabolism towards less estrogenic metabolites.
, and drugs, into water-soluble, excretable metabolites.
, and drugs, into water-soluble, excretable metabolites.
mtolmetin guacil hydrolysed in to following metabolites Tolmetin, MED5 and Guiacol.
for biological samples, when analyzing for metabolites, since the metabolic process generally resu
tment of poisons that are definitely fungal metabolites causing noteworthy health problems for huma
Triacsin C belongs to a family of fungal metabolites all having an 11-carbon alkenyl chain with
me synthetic opioids such as pethidine have metabolites which are actually neurotoxic and should th
in two inactive conjugated and hydroxylated metabolites (called metabolites 5 and 6).
In humans, cyanohydrins are important metabolites in cyanide detoxification processes.
g with lower concentrations of the inactive metabolites, N-Desmethoxypropylbrinzolamide and O-Desme
cal tissues, and ultimately become inactive metabolites in the liver.
3,6-diglucuronide, both considered inactive metabolites).
orphine, as well as some otherwise inactive metabolites like morphine-3-glucuronide, have been foun
nitrenium, carbonium and arylamidonium ion metabolites of 2-AAF react with the nucleophilic groups
IL-1b) induced changes in dopamine and it's metabolites in the shell of the Nucleus accumbens.
adiolabled isotopes, difenacoum (and/or its metabolites) has been shown to be distributed across ma
e pharmacological effects of a drug and its metabolites on target and off-target organs as well as
not known whether ulipristal acetate or its metabolites are excreted into the breast milk.
he banned stimulant methamphetamine and its metabolites during his national time trial championship
EPA and its metabolites act in the body largely by their interactio
beetle, are reported to use phytol and its metabolites (e.g.
also cause accumulation of the drug and its metabolites in the excretory system.
mall amounts of metaclazepam as well as its metabolites enter into human breast milk.
ardiotoxic effect in higher doses while its metabolites have no such effect.
The amount of 4-aminobenzoic acid and its metabolites excreted in the urine is taken as a measure
However, Brinzolamide's other known metabolites (N-Desmethoxypropylbrinzolamide and O-Desme
hich inhibit HMG-CoA reductase, lapaquistat metabolites inhibit squalene synthase, which is further
for the metabolism of morphine to the main metabolites, morphine-3-glucuronide (M3G) which has no
The two main metabolites are desmethyldoxylamine and didesmethyldoxy
The main metabolites of Prajmaline are: 21-carboxyprajmaline and
dihydroxy-2-hexanone, it is one of the main metabolites of hexane.
Likewise, the two main metabolites - coelenteramide and coelenteramine - were
The main metabolites excreted in the urine of humans exposed to
et al. (1991), demonstrated that the major metabolites alpha-methyldopamine (α-MeDA) and 3-O-methy
All of the major metabolites are unhydrolyzed carbamates.
DM and its major metabolites were measured in urine.
desalkyl-2-oxoquazepam) is one of the major metabolites of quazepam.
hat transport in a highly controlled manner metabolites across this membrane.
that both inorganic arsenic and methylated metabolites cross the placenta to the fetus, however, t
ne, imidacloprid urea as well as five minor metabolites.
a pro-drug, it is morphine and other minor metabolites that actively bind with μ-opioid receptors.
uch, it is essential for the uptake of most metabolites, and also for plant responses to the enviro
e methylenedioxy ring, producing neurotoxic metabolites such as alpha-Methyldopamine, it was hoped
activity of isolated enzymes to produce new metabolites, to allow new (catalyzed) pathways for reac
shown in blue and purple lead to non-toxic metabolites; the pathway in red leads to toxic NAPQI.
movement aids in the delivery of nutrients, metabolites, genetic information, and other materials t
n the rats' guts may alter the formation of metabolites of caffeic acid.
ever, the authors did not detect binding of metabolites related to this pathway (L-ornithine, L-lys
rs to molecules which are the precursors or metabolites of biologically significant molecules.
material that detects certain molecules or metabolites.
in urinary concentration of organophosphate metabolites was associated with a 55% to 72% increase i
sed synthesis of organic compounds or other metabolites for fungal growth, including the chemical i
Other metabolites such as the N,O-glucuronide, although not d
ce it is synthesized in the body from other metabolites, including glycine.
ions with other lipids, proteins, and other metabolites.
are significant as cytochrome P450 oxidase metabolites of unsaturated carbon-carbon bonds, but are
concept to suggest that " ....active oxygen metabolites act as specific intermediary transmitter su
The neurotoxicity of pethidine's metabolites is a unique feature of pethidine compared t
Pethidine's metabolites are further conjugated with glucuronic acid
It binds to vitamin D and its plasma metabolites and transports them to target tissues.
d glutaconic acids are structurally related metabolites.
arasite through the production of secondary metabolites.
uce polyketides, a large class of secondary metabolites, in bacteria, fungi, plants, and a few anim
systems as a source of high-value secondary metabolites (drugs).
Ansamycins is a family of secondary metabolites that show antimicrobial activity against ma
Most of the secondary metabolites of interest to humankind fit into categorie
s a group of bacterial polyketide secondary metabolites containing a diazo group.
Secondary metabolites (alkaloids) from marine sponges stimulate n
tion was used in the synthesis of secondary metabolites such as actinophyllic acid.
class of sugar-derived microbial secondary metabolites that demonstrate significant biological act
mammals, and are considered to be secondary metabolites.
ve been found to contain the rare secondary metabolites naphthoquinone, glucosides, droserone, hydr
Since secondary metabolites are often created by modified primary metab
oids are a class of alkaloids and secondary metabolites that contain a tropane ring in their chemic
their lipopolysaccharides or into secondary metabolites such as antibiotics.
Many secondary metabolites from endophyte-plant interactions have also
ike most pharmacologically-active secondary metabolites of plants, THC in cannabis is assumed to be
ass of low molecular weight plant secondary metabolites that are produced during infection.
been firmly established, there are several metabolites worthy of note.
void overflow metabolism (formation of side metabolites, such as acetate for Escherichia coli, lact
would constitute the complete pool of small metabolites in a cell at any given time and this would
ns typically control the diffusion of small metabolites like sugars, ions, and amino acids.
cular-scale entities such as ions, solutes, metabolites, lipids, proteins, etc.
Some metabolites may have unwanted side effects.
Sphingolipid metabolites, such as ceramide, sphingosine and sphingos
vices include synthesis of drug substances, metabolites, impurities, and degradants (including stab
vent flushing by being broken down into the metabolites Niacin (aka Nicotinic acid) and Inositol at
One of the metabolites of cistracurium via Hofmann elimination is
The toxic effects mediated by the metabolites cannot be countered with opioid receptor an
f chemodegradation: consequently one of the metabolites from this process is laudanosine, a tertiar
The metabolites also are excreted unchanged in the urine.
The metabolites lack the specific biological activity of ca
The metabolites are found in feces and urine.
The metabolites are excreted in the urine and feces.
e rats performed better after receiving the metabolites, suggesting that the metabolites reduced ox
f the remaining 10% of the drug none of the metabolites showed any pharmacological activity.
One of the metabolites of fipronil has a higher toxicity to birds
ential to interact with NSAIDs and/or their metabolites, resulting in antagonism of GABA neurotrans
circulation of some drugs/toxins and their metabolites
measurement of xenobiotics (drugs and their metabolites, and biological molecules in unnatural loca
te detection of banned substances and their metabolites through analysis, using gas chromatography
e are variable results about which of these metabolites is most important, as some studies have sho
These metabolites are more potent than the parent drug.
Mesna assists to detoxify these metabolites by reaction of its sulfhydryl group with th
to introduce the use of NMR to study tissue metabolites.
peroxide, leading to the formation of toxic metabolites which destroy dopamine storage vesicles in
structure are notorious for producing toxic metabolites.
definitely due to the gradual rise in toxic metabolites, use of nutrients and increase in cell numb
ating culture, fresh nutrients and no toxic metabolites allowing continued growth of the cells with
The other two metabolites are alpha-hydroxyalprazolam and estazolam.
ugs, or reducing the production of unwanted metabolites.
be monitored by measurement of the urinary metabolites, while severe overdosage may be confirmed b
ents, in vivo, may be converted to urotoxic metabolites such as acrolein.
The major function of JA and its various metabolites is regulating plant responses to abiotic an
It can be inferred that its in vivo metabolites may have stronger effects on the reuptake o
                                                                                                   


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