「insulin」の共起表現(2語右で並び替え) - Weblio英語共起表現検索


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「insulin」の共起表現一覧(2語右で並び替え)

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a few years earlier, before the discovery of insulin, such a diagnosis would have been a death sen
Collip's task was to prepare insulin in a more pure, usable form than Banting and
researchers responsible for the discovery of insulin as a treatment for diabetes.
, and ultimately resulted in the discovery of insulin as a treatment for the disease.
Sanger's initial results suggested that insulin was a smaller molecule than previously estima
eam by the β-cells of the pancreas along with insulin, after a meal.
are autosomal recessive condition associating insulin resistance, absence of subcutaneous fat and m
n the Insulin-Receptor Gene in a Patient with Insulin Resistance, Acanthosis Nigricans, and the Pol
His results synthesizing insulin were achieved almost simultaneously with that
erregulatory hormones, opposing the action of insulin, i.e. acting against the hypoglycemia.
Known as “The Birthplace of Insulin”, 442 Adelaide St. N. in London, Ontario is t
Dr. Frederick Banting, who in 1922 discovered insulin, and all the people that have lost their live
Insulin degludec also has the ability to be mixed wit
ubjects experienced weight loss and decreased insulin resistance, although the mechanism was unknow
ows continued signal output (e.g., to trigger insulin release) amid significant amounts of its prod
e able to sense the glucose level and produce insulin, the amount of insulin secreted is usually th
catabolic hormone that opposes the effects of insulin and amylin.
genes such as those for H-ras, c-myb, and the insulin receptor,, and genes encoding housekeeping en
stosterone, lowered blood pressure, increased insulin sensitivity and a corresponding improvement i
receptor binding, but blocks the formation of insulin dimers and hexamers.
current marketed long-acting insulins such as Insulin glargine and Insulin detemir.
he relaxin-like peptide family belongs in the insulin superfamily and consists of 7 peptides of hig
Normal insulin secretion and blood levels are closely relate
Pyruvate dehydrogenase is stimulated by insulin, PEP, and AMP, but competitively inhibited by
influence of FSH on Sertoli cell, enhanced by insulin, retinol, and testosterone.
increase high blood pressure include obesity, insulin resistance and high cholesterol levels.
Kv1.3 promoter region is associated with low insulin sensitivity and impaired glucose tolerance.
th PCOS (polycystic ovary syndrome) to reduce insulin problems and possibly improve fertility.
ally known as the one of the largest users of insulin pump and real-time glucose sensing devices in
-glucose pentaacetate, was found to stimulate insulin release, and might therefore be of therapeuti
ets, it serves as a glucose sensor to control insulin release, and similarly controls glucagon rele
ALCAR has also been shown to improve insulin response and is proved to have a positive eff
irectory of selected over-the-counter agents, insulin formulations, and prescription drug products,
This suggests chemerin plays a role in insulin sensitivity and may be a potential therapeuti
Blood sugar is regulated by insulin, glucagons, and other hormones that control i
ition, the Cideb null mice also have improved insulin sensitivity and enhanced hepatic fatty acid o
Beta cells ( insulin secretory) and delta cells (somatostatin secr
In animal studies it was found to improve insulin sensitivity and lower plasma glucose levels i
metabolic syndrome, including higher fasting insulin, glucose, and triglycerides, and lower HDL-ch
It also activates insulin receptor and has insulin-mimetic effects, low
uding regulation of vascular and airway tone, insulin secretion, and peristalsis.
sole interest in C-peptide was as a marker of insulin secretion and has as such been of great value
human serum albumin, human transferrin, human insulin, but animal-derived lipids (as with StemPro 3
nology and the production of proteins such as insulin that are important for medical treatments of
Insulin syringes are marked in insulin "units".
Insulin injections are intended to induce hypoglycemi
pression of the receptors are correlated with insulin levels, as well as reduced in mouse models of
t, Morrison regulates his blood sugar with an insulin pump attached to his abdomen.
Glory Enough for All depicted the search for insulin by Banting and Best, with R. H. Thomson starr
is allowed larger amounts of active monomeric insulin to be immediately available for postprandial
he underlying DNA, the amino acid sequence of insulin can be changed to alter its ADME (absorption,
chemist who participated in the sequencing of insulin, and became Austria's first university profes
The statement that ' insulin has been strongly preserved' is vague, as it
for the murder of an 80-year-old patient with insulin, has been identified as a possible inspiratio
on 21 March 1991, due to Allitt administering insulin overdoses, before he was transferred to anoth
ss by which serotonin controls the release of insulin from beta cells in the pancreas and so the re
who don't have diabetes, apparently by making insulin work better."
Researchers found improvements in insulin, triglycerides, blood sugar levels, and infla
als work exclusively to provide medical care, insulin dosing, blood sugar corrections, nighttime bl
ia, while Nicolae Paulescu, the discoverer of insulin, was born in Bucharest, Romania.
r form of the disease, in which there is some insulin resistance but normal growth and subcutaneous
ht to have the smallest effects on weight and insulin resistance, but clinical experience with thes
r, increase lypolysis in fat tissue, increase insulin sensitivity by increasing glucose transporter
eins and may be involved in the regulation of insulin secretion by glucose.
MUC1, Mammalian target of rapamycin, RASGRP3, Insulin receptor, C1QBP, PLD2 and SHC1.
Insulin aspart can be used in CSII pumps and Flexpen,
The prolonged elevation of insulin levels can lead to dyslipidemia.
sphorylation of IRS-1, thereby inhibiting the insulin signalling cascade.
for example on the peripheral cells (e.g. the insulin releasing cells of the pancreas) and on the c
oblastoma, which is an abnormal growth of the insulin secreting cells in the pancreas.
rodents, while also remembering to take their insulin and check their blood glucose.
the body attacks the cells producing insulin, the chemical that allows the metabolizing of
human serum albumin, human transferrin, human insulin, and chemically defined or human lipids.
Some types of insulin solution contain metacresol.
iling health; a diabetic, she is dependent on insulin to control her condition but has to obtain su
bit glucagon release, which in turn increases insulin secretion, decreases gastric emptying, and de
nto almost any organ-and coax them to produce insulin in diabetics.
Sanger continued work on insulin, using dinitrofluorobenzene in combination wi
plex, bis(allixinato)zinc(II), shows the same insulin mimetic effects.
was hypothesized that the grapefruit reduced insulin levels, encouraging fat loss.
pics included Banting and Best's discovery of insulin, the establishment of Montreal, the RCMP Musi
increases beta cells mass and insulin gene expression, post-translational processin
nt linker between the A- and the B- chains of insulin and facilitates the efficient assembly, foldi
betes by control of the upstream activator of insulin growth factor-1 (IGF-1) and mitogen-activated
The activity of this complex is stimulated by insulin, growth factors, serum, phosphatidic acid, am
so appears to have a beneficial effect on the insulin resistance featured by the metabolic syndrome
greatest effects on weight gain and decreased insulin sensitivity, followed by risperidone and quet
Meanwhile, Poe, seeking an insulin shot for Baby-O, meets Larkin and the two run
ns with GAD65 has been shown to preserve some insulin production for 30 months in humans with type
periments had included patients' having their insulin withheld for two days, during which time they
ased at low temperature and a special form of insulin allows for this extra glucose to enter the ce
egend of Big Paw requires the extra dosage of insulin reserved for such treks into celluloid and co
Animas produces and develops insulin pumps for people with diabetes.
descendants, Charles Herbert Best, discovered insulin with Frederick Banting.
The increase in calcium will initiate more insulin release from each beta cell.
former student of his father, on cloning the insulin gene from carp.
e-1 diabetes mellitus, the disease-associated insulin- and GAD65-specific T cells isolated from the
AMPA iGluRs modulate the secretion of insulin and glucagon in the pancreas, opening the pos
e primary regulators of this are the hormones insulin and glucagon, which affect the enzyme through
ceptor gamma (PPAR-γ), a central regulator of insulin and glucose metabolism.
cogen storage levels, and this indicates that insulin activates glycogen synthase by inhibiting its
In this roundabout manner, insulin increases glycogen synthesis.
ations should be coupled with a longer acting insulin for good glycemic control.
o coax bacteria into creating synthetic human insulin, human growth hormone, and human TPA for use
ic hypoglycaemia, induced by an over-generous insulin and had not neutralised its effects with food
Insulin receptor has been shown to interact with Ecto
Insulin lispro has one primary advantage over regular
Alex because of his diabetes, and his lack of insulin could have resulted in a coma or even death.
sugar by stimulating the pancreas to secrete insulin and helping the body use insulin efficiently.
: those tending toward reduced sensitivity to insulin and high blood glucose levels (hyperglycemia)
rics and orthopedic surgery, the discovery of insulin attracted him to internal medicine, specifica
ce 1935, metrazol, an epileptogenic drug, and insulin, a hormone, were in wide use in many countrie
roducts and/or processes, including synthetic insulin, growth hormone, and TPA, often beating out b
Lilly produces synthetic, recombinant 'human' insulin, branded Humulin
f polycystic ovary syndrome (PCOS), including insulin resistance, hyperandrogenism, and oligo-ameno
ients, ketoacidosis is usually accompanied by insulin deficiency, hyperglycemia, and dehydration.
ribute to hyperuricemia, including: genetics, insulin resistance, hypertension, renal insufficiency
It is assumed that the ability to respond to insulin induced hypoglycemia translates into appropri
moderate mental retardation, hypothyroidism, insulin resistance, hypoparathyroidism.
ncentration of HDL cholesterol increased, and insulin resistance improved much more in dieters foll
nts”, Somogyi first presented his theory that insulin treatment in itself might cause unstable diab
Cameron also induced insulin comas in his subjects by giving them large in
here is also evidence that it plays a part in insulin sensitivity in other cells.
vo Nordisk hopes to begin marketing the novel insulin analog in 2013.
H) in response to the hypoglycaemia caused by insulin, rises in prolactin and thyroid-stimulating h
from the Surviving Sepsis Campaign recommend insulin therapy in critically ill patients.
This causes only intermittent secretion of insulin, usually in response to stress.
Harold Bourne published a paper entitled "The insulin myth" in the Lancet, in which he argued that
K has been shown to stimulate dose-dependent insulin secretion in rats, though no hypoglycemia was
It has also been applied to the study of insulin secretion in beta cells of the pancreas.
that codes for a zinc transporter related to insulin secretion in humans.
it may improve glycemic control and decrease insulin resistance in people with poorly controlled t
his gene has been associated with obesity and insulin resistance in children.
reatment of obesity, for enhancing peripheral insulin sensitivity in patients with type-2 diabetes
etic, the 30-year-old father searched for his insulin pen in the capsized ship; however, for the fi
eir blood sugars in normal ranges, and 44% on insulin left insulin-free.
The main activity of activation of the insulin receptor is inducing glucose uptake.
Insulin degludec is currently in Phase III clinical t
The pH of insulin aspart is 7.2-7.6.
Insulin degludec is a novel ultralong-acting basal in
In molecular biology, the insulin receptor is a transmembrane receptor that is
Like insulin, amylin is deficient in individuals with diab
Hyperinsulinism due to reduced insulin sensitivity is usually asymptomatic.
An insulin analog is an altered form of insulin, differe
This can change the potency of the insulin, and it would no longer be as effective.
delay progress to diabetes, and in those with insulin resistance it slowed progress in the HOMA sev
ic islets of Langerhans produced and exported insulin, and it steadily pushed Lacy up through the a
e worked on the amino acid sequence of bovine insulin, sequencing its beta chain.
To date, only leptin and insulin are known to act as an adiposity signal.
1982 Genentech synthetic 'human' insulin approved, largely thanks to its partnership w
n credited with being the first to synthesize insulin while leading a team at the University of Pit
de production, nerve growth factor synthesis, insulin resistance, loss of mean body mass, and IL-8
To generate the bioactive form of insulin (and many other peptides), a second step invo
l understood link between central obesity and insulin resistance; marked peculiarities of T2DM.
e reason, preproinsulin is rarely used unlike insulin, the mature product, and proinsulin, a stable
nage blood sugar: on condition that providing insulin stimulating meds or meds that sensitizes the
Studies have shown that patients taking insulin degludec needed to take significantly smaller
ulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial
ve shown that there is no difference, however insulin should not be stored in intense heat for a lo
ntaining vesicles with the cell membrane, and insulin secretion occurs.
lood type tests in Norway in 1919, as well as insulin treatment of diabetes patients in Norway.
The first insulin treatment of a child with diabetes in the USA
Allitt attempted to murder him with an insulin overdose on three occasions that day before h
1922 Banting and Best use bovine insulin extract on human
tions were focal, involving overproduction of insulin by only a portion of the pancreas.
ea made from the tree is said to be a natural insulin substitute or "vegetable insulin" that is cap
enentech's approach to the first synthesis of insulin won out over Wally Gilbert's approach at Biog
His approach to the first synthesis of insulin lost out to Genentech's approach which used g
ers blood sugar by stimulating the release of insulin by pancreatic beta cells and by inducing incr
The Insulin Signaling Pathway
adhesion, b cell receptor signaling pathway, insulin signaling pathway, melanogenesis, alzheimer's
e participates in fatty acid biosynthesis and insulin signaling pathway.
m of action by which these complexes regulate insulin signaling pathways is unclear.
When they were not in a coma, insulin coma patients were kept together in a group a
dren, and Barbara is a diabetic who needs two insulin shots per day.
en by international experts in endocrinology, insulin resistance, prediabetes, metabolic syndrome a
mia are are quite variable, and so suicide by insulin is probably less reliable than a gun or poiso
include glutathione-insulin transhydrogenase, insulin reductase, reductase, protein disulfide (glut
or better fabric and paper, microcapsules for insulin sustained release and cancer drug nanocapsule
by removal of the signal peptide and then to insulin by removal of the connecting peptide (C-pepti
lowing slightly more flexibility than regular insulin, which requires a longer waiting period befor
in metabolic control in many animals, whether insulin per se is important in ALL animals is, I beli
High insulin levels seem the likely link between metabolic
plemented with bovine or human serum albumin, insulin, transferrin, selenium and a thiol such as 2-
y appeared to admit many different molecules ( insulin, bovine serum albumin, gold nanoparticles) le
For this reason " insulin insensitivity", or a decrease in insulin rece
andful of exceptions - notably nitroglycerin, insulin and some liquid antibiotics - most expired dr
oli with the specific task of producing human insulin from starting amino acids is an example.
region (ILPR) is a regulatory sequence on the insulin gene starting at position -363 upstream from
This insulin secretion subsides as blood glucose concentra
vival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway.
all mortality by about 30% when compared with insulin and sulfonylureas (glibenclamide and chlorpro
rds a similar level of blood sugar control to insulin and sulfonylureas, it appears to decrease mor
pupil who will go as far as refusing to take insulin so that she can lose weight, to be "Rochdales
It is claimed to help build up insulin in the human body and is sometimes referred t
This 2-component insulin retains the ultralow risk characteristics of
s blood glucose by stimulating the release of insulin from the pancreas.
Hypoglycemia due to excess insulin is the most common type of serious hypoglycem
Diazoxide also inhibits the secretion of insulin from the pancreas, thus it is used to decreas
As a phosphoprotein phosphatase, insulin dephosphorylates the enzyme, thus activating
                                                                                                   


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