「selectivity」の共起表現(1語右で並び替え)

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「selectivity」の共起表現一覧(1語右で並び替え)

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-HT1A receptor agonist with some functional	selectivity, acting as a full agonist at presynaptic an
This	selectivity allows some parts of the object being heate
are added to the electrodes to enhance the	selectivity and stability.
difficult to prepare, but offer much better	selectivity and strength of binding than other complexa
ignant tissue and this is the basis for its	selectivity and pharmacokinetic properties.
oduces two products which differ in peptide	selectivity and level of restoration of surface express
ods are more expensive, thus encourage more	selectivity and additional consideration.
ecular systems and mechanisms for dynamical	selectivity and specificity".
rat recombinant systems, showing functional	selectivity and stimulating one type of G-protein coupl
le and organic concentration, and pH on the	selectivity and resolution of seven barbiturates.
yl group, generally confers significant CB2	selectivity, but reasonable CB1 affinity and selectivit
ion was found to retain 5-HT2A affinity and	selectivity, but reversed activity from an antagonist t
ysts is not only detrimental to the product	selectivity, but also presents a challenge for the reac
It displays functional	selectivity by strongly activating 5-HT1A receptors in
properties including pore conductance, size	selectivity, charge selectivity, voltage gating, and ch
n particular limitations, such as with true	selectivity, clogging and, more undetectably, they prov
A	selectivity coefficient is defined as the ratio of the
In ion-exchange chromatography the	selectivity coefficient is defined in a slightly differ
Due to its	selectivity, DOM is often used in scientific research w
s often suffers from reduced reactivity and	selectivity due to the fact that the catalytic active c
low sequence conservation, which determines	selectivity during protein-protein interactions (Bolano
not to evolution but rather to hydrodynamic	selectivity, ecologic habitats, and differential mobili
ξ is the	selectivity factor
he combination of the ripple factor and the	selectivity factor specify the stopband ripple.
other subunits, and together they form the	selectivity filter region of the channel pore.
rapping introduces a new binding mode and a	selectivity filter to broaden the universe of molecular
The pore of sodium channels contains a	selectivity filter made of negatively charged amino aci
in all potassium ion channels and forms the	selectivity filter that enables the channel to transpor
A K+ channel pore domain (S5,	selectivity filter, and S6).
pore, including the fundamental ideas of a	selectivity filter, a wider inner vestibule and a gate
SCH-23,390 - 100-fold	selectivity for D1 over D5
de is a dopamine antagonist with reasonable	selectivity for the D3 subtype (9.6 times selectivity f
a sigma receptor antagonist, with moderate	selectivity for the σ1 subtype.
lity at X can increase both the potency and	selectivity for H1-receptors
It has approximately 10-fold	selectivity for D1 and D5 over the D2 receptor.
High product	selectivity for formate and formic acid (up to 90%)
ntanil is a fentanyl derivative with strong	selectivity for the μ opioid receptor.
ds are known, almost all of which have high	selectivity for CB2.
In rat neurons, less	selectivity for kurtoxin on calcium channels is found.
the mu and delta opioid receptors, showing	selectivity for the delta receptor.
ve, with its 2-methyl derivative having 40x	selectivity for CB2.
eptor antagonist with approximately 10-fold	selectivity for the former site over the latter.
d epinephrine, with a significantly greater	selectivity for serotonin.
sion and orthostatic hypotension due to its	selectivity for α1a-adrenergic receptors.
nicotinic acetylcholine receptors with high	selectivity for the α4β2 subtype.
mains in that they show wide range of lipid	selectivity for the major components of cell membranes,
It has a much higher	selectivity for δ opioid receptors than μ receptors, an
n agonist at both CB1 and CB2 with moderate	selectivity for CB1, with a Ki of 22.3nM at CB1 and 58.
It is not known whether this	selectivity for the M3 receptor translates into any cli
holecystokinin antagonist, with fairly high	selectivity for the CCKA subtype.
t agonist at both CB1 and CB2 with moderate	selectivity for CB1, with a Ki of 0.4nM at CB1 vs 1.9nM
ro substitution instead confers significant	selectivity for CB2.
isoform of 5α-redcutase, with about 15-fold	selectivity for it over type I isoform of the enzyme.
tone-deaf, while crickets and mantids show	selectivity for sound frequency.
SKF-83,959 - 7-fold	selectivity for D1 over D5 with negligible affinity for
Lastly AH-1058 displays a greater	selectivity for cardiac tissue over verapamil and ateno
-40503 is a SARM that shows good functional	selectivity for bone tissue, and has relatively little
tylcholine receptor agonist with reasonable	selectivity for the M1 and M4 subtypes, though it is al
rexin receptor subtype OX1, with around 70x	selectivity for OX1 over OX2 receptors, and improved or
he CB1 and CB2 receptors, but with moderate	selectivity for CB2, having a Ki of 5.44nM at CB2 vs 20
to the related FID detector which lacks the	selectivity for nitrogen and phosphorus.
s as a cannabinoid agonist with about 1.75x	selectivity for CB2 with a Ki of 90nM ± 17 and 159nM ±
3-carboxylic acid core structure, with 190x	selectivity for CB2 over the related CB1 receptor.
It displays high	selectivity for MAGL over other brain serine hydrolases
serotonin receptor subtypes, with moderate	selectivity for 5-HT2C, but relatively low affinity for
to the dopamine transporter with increased	selectivity for the norepinephrine transporters.
amine transporters although still with some	selectivity for the dopamine transporter.
ound that eotaxin-1 (CCL11) has high degree	selectivity for its receptor, such that they are inacti
The channels vary in	selectivity for the permeating ions from nonselective b
acts as a cannabinoid agonist with about 5x	selectivity for CB1 with a Ki of 29nM and 146nM at CB2.
at the CB1 receptor, giving it around 180x	selectivity for CB2.
However despite this relatively high	selectivity for CB2, its CB1 affinity is still too high
ts as a cannabinoid agonist with about 2.4x	selectivity for CB1 with a Ki of 8.4nM ± 1.8 and 20nM ±
rexin receptor subtype OX1, with around 50x	selectivity for OX1 over OX2 receptors.
ies of ionotropic glutamate receptors, with	selectivity for the GluR5 subtype of the kainate recept
rboxamide at 2β, RTI-229 has extremely high	selectivity for the dopamine transporter (2600x and 460
tives have been developed with much greater	selectivity for butyrylcholinesterase, and both cymseri
frequencies of 9 MHz or 10.7 MHz to provide	selectivity in communications receivers, or at higher f
ters tend to be used at 10.7 MHz to provide	selectivity in broadcast FM receivers, or at a lower fr
Due to its	selectivity in blocking the beta1 receptors in the hear
cey" feeling, which were attributed to poor	selectivity in vivo over the hallucinogenic 5-HT2A rece
en the carbene is stabilized by a metal the	selectivity increases.
However, the degree of size	selectivity is restricted by the hiding effect describe
	Selectivity is achieved at mildly basic solutions (pH 7
This lack of receptor	selectivity is the basis of the poor tolerability profi
expression systems and therefore functional	selectivity is not just an epiphenomenon of one particu
uninfected cells, however the mechanism of	selectivity is not known.
n similar reaction, however, with increased	selectivity: it allows the synthesis of asymmetric bis
a venous dosing, and acyclovir has a higher	selectivity, lower inhibitory concentration and higher
ke transporter, with its extremely high DAT	selectivity making it useful for distinguishing between
Therefore greater GPCR	selectivity may be obtained by targeting allosteric sit
st, though based on its effects profile its	selectivity may be considered controversial.
The	selectivity of penciclovir may be attributed to two fac
The	selectivity of the hydrozirconation of alkynes has been
ective for the CB2 receptor subtype, with a	selectivity of over 5000x for CB2 vs CB1.
It improves the	selectivity of lithiation reactions by breaking up the
Further improvements can be made to the	selectivity of MEKC by adding chiral selectors or chira
0.00035nM) and a	selectivity of over 60,000x for CB1 over CB2.. Independ
rbon tail needs to be short to maximize the	selectivity of the desired mineral and the headgroup di
By existing in proximity, the speed and	selectivity of binding interactions between enzymatic c
The	selectivity of undergraduate institution is also a pred
difference is important for maintaining the	selectivity of valinomycin for the transport of potassi
s noted as the best detergent for improving	selectivity of immunoprecipitation of phosphotyrosine m
que is used mainly to enhance retention and	selectivity of various solutes that would otherwise be
ng affinity at CB1, explaining the high CB2	selectivity of AM-1221.
retention of an analyte and can change the	selectivity of certain analytes.
eptor subtype OX2, with an IC50 of 40nM and	selectivity of around 250x for OX2 over OX1 receptors.
This domain is responsible for the	selectivity of the protein and consists of two subdomai
2 receptor agonist, with a Ki of 13.0nM and	selectivity of around 220x for CB2 over CB1 receptors.
es it useful for distinguishing the subtype	selectivity of drugs acting at the δ receptors.
ty is reduced much more, resulting in a CB1	selectivity of around 13x.
e in catalytic activity (up to 90-fold) and	selectivity of a gas exposed electrode on a solid elect
with random dot stimuli to study disparity	selectivity of neurons since the lateral distance requi
ist for the serotonin receptor 5-HT5A, with	selectivity of around 100x over other serotonin recepto
d that the regioselectivity and atropisomer	selectivity of these probable one-electron coupling rea
and selective 5-HT3 partial agonist, 1000x	selectivity over other serotonin receptors
high affinity and efficacy at A2B, but poor	selectivity over other adenosine receptor subtypes
ceptor agonist, with an EC50 of 1nM and 15x	selectivity over 5-HT2A, although it only has moderate
at the serotonin 5-HT2B receptor, with good	selectivity over the related 5-HT2A and 5-HT2C receptor
in receptor subtype 5-HT1D, with around 60x	selectivity over other related receptors.
st for the adenosine A3 receptor, with high	selectivity over the other three adenosine receptor sub
T2B / 5-HT2C agonist, and while it has good	selectivity over 5-HT2A and other serotonin receptor su
-HT7 serotonin receptor subtypes, with good	selectivity over other receptors.
r agonist, with approximately 150x and 200x	selectivity over the closely related 5-HT1D and 5-HT1A
e receptor like-1) receptor, with over 100x	selectivity over other opioid receptors.
erotonin 5-HT2B receptor, with around 1000x	selectivity over the closely related 5-HT2A and 5-HT2C
B and 5-HT2C serotonin receptors, with good	selectivity over other serotonin receptor subtypes and
st at the related D3 subtype, but with good	selectivity over D4 and other unrelated receptors.
tor Y5, with a Ki of 1.5nM and around 3300x	selectivity over the related Y1, Y2 and Y4 receptors.
r more selective for 5-HT1A with over 1000x	selectivity over other serotonin receptor subtypes and
HT2C serotonin receptor subtypes, with good	selectivity over the closely related 5-HT2A subtype, an
tor CB1, with a Ki of 0.08nM at CB1 and 18x	selectivity over the related CB2 receptor.
ist for the 5-HT1A receptor and retains the	selectivity over the 5-HT2A/2C receptors.
r 5-HT2A, with a Ki of 2.0 nM, and moderate	selectivity over the related 5-HT2B and 5-HT2C receptor
tor agonist, with approximately 25x and 40x	selectivity over the closely related 5-HT1D and 5-HT1A
ptor CB2, with a Ki of 3.4nM at CB2 and 80x	selectivity over the related CB1 receptor.
urther development on the basis of its high	selectivity over related receptors, ease of synthesis,
2B binding affinity (Ki) of 3.4nM, and high	selectivity over the closely related 5-HT2A and 5-HT2C
serotonin 5-HT2C receptor, with around 100x	selectivity over the closely related 5-HT2A and 5-HT2B
ure, possibility of large-scale production,	selectivity, performance under extreme conditions and p
Functional	selectivity posits that a ligand may inherently produce
e most peptide compounds, had problems with	selectivity, potency, solubility and bioavailability.
According to the 2011 college	selectivity ranking by U.S. News & World Report, which
to track the RF and LO stages; the onerous	selectivity requirements are confined to the IF amplifi
Because of their reversibility and	selectivity, RIMAs are safer than the older monoamine o
High	selectivity semipermeable membranes, permeable for carb
sor (which are typical of many sensors) are	selectivity, sensitivity, stability, reproducibility, r
The	selectivity sequence, SVGFG, is very similar to that co
contains a number of compounds with varying	selectivity, several of which are either already in cli
in layers introduce defects that may affect	selectivity, so system design usually trades off the de
This gives AM-4030 a greater degree of	selectivity, so while it is still a potent agonist at b
Another type of pharmacological	selectivity that is unique to allosteric modulators is
Owing to this	selectivity, the reagent is ideal for reductive aminati
If the two solvents show different	selectivity, then the spots may be spread over the enti
one type of separation provides sufficient	selectivity, there are many analytical situations where
self an essential specificity factor in ion	selectivity, though that does not exclude it being part
lective D1 agonist with similar potency and	selectivity to SKF 89,145.
t binds as an agonist with high potency and	selectivity to mu Opioid receptors.
It is known to have a higher	selectivity to etch highly p-doped silicon than the mor
s actually show a very similar SERT/DAT/NET	selectivity to cocaine, although in vivo they behave di
e it has a high level of safety and a great	selectivity to act on the bulbar centre of cough.
These show some	selectivity towards IGF-1R over IR.
D2 dopamine receptor antagonist, with high	selectivity towards D3 receptors.
ial ligands for radioisotope delivery, with	selectivity towards hypoxic tissues, particularly in th
rapy, observing that their cytotoxicity and	selectivity towards cancer cell is higher than that of
grees Celsius providing enhanced control in	selectivity was introduced.
The molecular basis of ionic	selectivity were are also identified in the transmembra
The key word for organic synthesis is	selectivity, which is necessary to obtain a high yield
f the alkyl groups are the major factors in	selectivity with these reagents.
the androgen receptor, producing functional	selectivity with effective dissociation of anabolic and
ticism given that the present time requires	selectivity with respect to topics and phrases.
roceeds with exceptional regio- and stereo-	selectivity, yielding only the Markovnikov alcohol.

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「selectivity」の共起表現一覧(1語右で並び替え)