出典:Wikipedia
出典:『Wikipedia』 (2011/01/05 02:25 UTC 版)
Embutramide (Embutane) is a potent sedative drug. It was developed as a general anaesthetic agent, but was found to have a very narrow therapeutic window, with a 50mg/kg dose producing effective sedation, but a 75mg/kg dose was fatal. Along with strong sedative effects, embutramide also produces respiratory depression and ventricular arrythmia. This meant that it has never been adopted for medical use as an anaesthetic as it is far too dangerous for this purpose, but instead is used for euthanasia in veterinary medicine, mainly for euthanising dogs. It is formulated as a combination product under the brand name Tributame, which also contains chloroquine and lidocaine.