出典:Wikipedia
出典:『Wikipedia』 (2011/07/23 19:34 UTC 版)
Loratadine (INN) is a second-generation H1 histamine antagonist drug used to treat allergies. Structurally, it is closely related to tricyclic antidepressants such as imipramine, and distantly related to the atypical antipsychotic quetiapine. It is marketed by Schering-Plough under several trade names such as Claritin, and by Shionogi in Japan. Loratadine is available as a generic drug and is marketed for its non-sedating properties. In a version named Claritin-D or Clarinase, the substance is combined with pseudoephedrine, a decongestant; this makes it useful for colds as well as allergies, but adds potential side-effects of insomnia, nervousness, and anxiety.