a member of a group of enzymes that can break down proteins, such as collagen, that are normally found in the spaces between cells in tissues (i.e., extracellular matrix proteins). because these enzymes need zinc or calcium atoms to work properly, they are called metalloproteinases. matrix metalloproteinases are involved in wound healing, angiogenesis, and tumor cell metastasis.
出典:Wikipedia
出典:『Wikipedia』 (2011/02/12 10:52 UTC 版)
Matrix metalloproteinases (MMPs) are zinc-dependent endopeptidases; other family members are adamalysins, serralysins, and astacins. The MMPs belong to a larger family of proteases known as the metzincin superfamily.