出典:Wiktionary
出典:『Wiktionary』 (2007/03/28 15:44 UTC 版)
neuroactive steroid (複数形 neuroactive steroids)
出典:Wikipedia
出典:『Wikipedia』 (2010/12/21 12:38 UTC 版)
Neuroactive steroids (or neurosteroids) rapidly alter neuronal excitability through interaction with neurotransmitter-gated ion channels. In addition, these steroids may also exert effects on gene expression via intracellular steroid hormone receptors. Neurosteroids have a wide range of potential clinical applications from sedation to treatment of epilepsy and traumatic brain injury. Ganaxolone, an analog of the endogenous neurosteroid allopregnanolone, is under investigation for the treatment of epilepsy.