出典:Wikipedia
出典:『Wikipedia』 (2011/05/27 21:18 UTC 版)
Podosomes are the primary sites of integrin stimulated actin polymerization in leukocytes of the monocytic lineage. B cells have also been reported to form podosomes. Podosomes are similar in composition and structure to the invadopodia found in fibroblasts transformed with the v-Src oncogene which are matrix-degrading and whose formation is associated with increased tumor cell invasiveness.