出典:Wiktionary
出典:『Wiktionary』 (2025/10/29 20:11 UTC 版)
polyglutamylation (uncountable)
出典:Wikipedia
出典:『Wikipedia』 (2010/04/12 17:59 UTC 版)
Polyglutamylation is a form of reversible posttranslational modification of glutamate residues seen for example in alpha and beta tubulins, nucleosome assembly proteins NAP1 and NAP2. The γ-carboxy group of glutamate may form peptide-like bond with the amino group of a free glutamate whose α-carboxy group can now be extended into a polyglutamate chain. The glutamylation is done by the enzyme glutamylase and removed by deglutamylase.