Wiktionary英語版

出典:Wiktionary

nicodicodeine

発音

名詞

nicodicodeine (uncountable)

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ウィキペディア英語版

出典:Wikipedia

Nicodicodeine

出典:『Wikipedia』 (2011/02/06 00:16 UTC 版)

英語による解説

ウィキペディア英語版からの引用
引用

Nicodicodeine is an opiate derivative developed as a cough suppressant and analgesic. Synthesized in 1904, it is not commonly used, but has activity similar to other opiates. Nicodicodeine is metabolised in the liver by demethylation to produce 6-nicotinoyldihydromorphine, and subsequently further metabolised to dihydromorphine. Since the final active metabolite is the slightly stronger opiate dihydromorphine rather than morphine, nicodicodeine can be expected to be marginally more potent and longer acting than nicocodeine. Side effects are similar to those of other opiates and include itching, nausea and respiratory depression.

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