出典:Wikipedia
出典:『Wikipedia』 (2011/06/06 13:42 UTC 版)
Prothrombin Complex Concentrate (PCC) (trade name Beriplex or Octaplex) is a combination of blood clotting factors II, VII, IX and X, as well as protein C and S. It reverses the effect of warfarin (a coumarin anti-coagulant) and is used in cases of significant bleeding in patients with a coagulopathy (INR > 8.0, prolonged prothrombin time, raised d-dimer). Examples include gastrointestinal haemorrhage or intracranial haemorrhage.