出典:Wiktionary
sortase (複数形 sortases)
出典:Wikipedia
出典:『Wikipedia』 (2011/07/12 22:01 UTC 版)
Sortase refers to a group of prokaryotic enzymes which catalyze the assembly of pilins into pili, and the anchoring of pili to the cell wall. They act as both proteases and transpeptidases. Sortase, a transpeptidase present in almost all Gram-positive bacteria, anchors a range of important surface proteins to the cell wall. Sortase homologues are found in almost all Gram-positives, a single Gram-negative (Shewanella putrefaciens) and an archaean (Methanobacterium thermoautotrophicum), where cell wall LPXTG-mediated decoration has not been reported.