試み, 試錬, 辛苦, 難儀, 試練, 荒波, 苦, 多難, 試煉, 惨苦, 労苦, 苦難, 苦患
visitation、 trial、 tribulation
an annoying or frustrating or catastrophic event
煩わしいかいらだたしいか壊滅的な出来事
his mother-in-law's visits were a great trial for him
義母の来訪は彼にとって大きな試練だった
life is full of tribulations
人生は苦難に満ちている
a visitation of the plague
疫病の訪れ