Upadacitinibとは 意味・読み方・使い方

名詞

upadacitinib (uncountable)

1. (pharmacology) A medication belonging to the class of Janus kinase inhibitors, used for the treatment of several immune-mediated diseases such as rheumatoid arthritis, ankylosing spondylitis, and atopic dermatitis.
   • 2021 December, Christine Liu, Jacqueline Kieltyka, Roy Fleischmann, Massimo Gadina, John J. O’Shea, “A Decade of JAK Inhibitors: What Have We Learned and What May Be the Future?”, in Arthritis & Rheumatology, volume 73, number 12, →DOI, page 2168:

     Upadacitinib monotherapy has also been shown to be more effective than MTX in MTX-naive patients with RA (24). Both upadacitinib and filgotinib have been referred to as “second-generation jakinibs” since they both preferentially inhibit JAK1 in vitro but their clinical efficacy and safety, to a large extent, is similar to pan-jakinibs in RA, […]