出典:Wiktionary
出典:『Wiktionary』 (2010/05/14 09:58 UTC 版)
nitisinone (uncountable)
出典:Wikipedia
出典:『Wikipedia』 (2011/05/19 10:45 UTC 版)
Nitisinone (also known as NTBC, an abbreviation of its full chemical name) is a drug originally developed as an herbicide now used in the treatment of hereditary tyrosinemia type 1. Since its first use for this indication in 1991 it has replaced liver transplantation as the first-line treatment for this rare condition. It is also being studied in the less severe but related condition alkaptonuria. It is marketed under the brand name Orfadin.