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topiramate

(抗てんかん薬)
トピラマート, トピラメート
関連語
  • Topamax
同義語(異表記)
2,3-4,5-bis-O-(1-methylethylidene)-
beta-D-fructopyranose sulfamate
Epitomax
McN 4853
McN-4853
Topamax
Topina
topiramate
USL255
トパマックス
トピナ
トピラマート
トピラメート
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Wiktionary英語版

出典:Wiktionary

topiramate

ウィキペディア英語版

出典:Wikipedia

Topiramate

出典:『Wikipedia』 (2011/07/19 08:42 UTC 版)

英語による解説

ウィキペディア英語版からの引用
引用

Topiramate (brand name Topamax) is an anticonvulsant (antiepilepsy) drug. It was originally produced by Ortho-McNeil Neurologics and Noramco, Inc., both divisions of Johnson & Johnson. It was discovered in 1979 by Bruce E. Maryanoff and Joseph F. Gardocki during their research work at McNeil Pharmaceutical. Generic versions are available in Canada and were FDA approved in September 2006. Mylan Pharmaceuticals was recently granted final approval for generic topiramate 25, 100, and 200 mg tablets and sprinkle capsules by the FDA for sale in the US. 50 mg tablets were granted tentative approval. The last patent for topiramate in the U.S. was for pediatric use; this patent expired on February 28, 2009. On May 21, 2010, Ortho-McNeil plead guilty and was fined US$6.14 million by the FDA for promoting Topamax to treat psychiatric disorders, without applying for any approval and there was no data from any well-controlled clinical trial to demonstrate that Topamax was safe and effective to treat any psychiatric conditions.

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