出典:Wiktionary
出典:『Wiktionary』 (2026/04/20 21:25 UTC 版)
abatacept (uncountable)
出典:Wikipedia
出典:『Wikipedia』 (2011/06/06 17:52 UTC 版)
Abatacept (marketed as Orencia) is a fusion protein composed of an immunoglobulin fused to the extracellular domain of CTLA-4, a molecule capable of binding B7. Abatacept is a selective costimulation modulator as it inhibits the costimulation of T cells. It was developed by Bristol-Myers-Squibb and is licensed in the United States for the treatment of rheumatoid arthritis in the case of inadequate response to anti-TNFα therapy.