英和和英

名詞

deimmunization

1. The process of deimmunizing.
   • 2015 June 17, Kristina Blazanovic et al., “Structure-based redesign of lysostaphin yields potent antistaphylococcal enzymes that evade immune cell surveillance”, in Molecular Therapy. Methods & Clinical Development^[1], volume 2, DOI:10.1038/mtm.2015.21:

     Mutations were restricted to those specified in the deimmunization prior, though all side-chains were allowed to change rotameric conformation in the search for low energy enzyme designs predicted to maintain the parental enzyme’s antibacterial activity.