rat | 遺伝子名 | Platelet-derived growth factor |
同義語(エイリアス) | Pdgfb; platelet derived growth factor, B polypeptide; SIS; c-sis; PDGF-2; Platelet-derived growth factor beta polypeptide; PDGF B-chain; Platelet-derived growth factor B chain precursor | |
SWISS-PROTのID | SWISS-PROT:Q05028 | |
EntrezGeneのID | EntrezGene:24628 | |
その他のDBのID | RGD:3283 |
本文中に表示されているデータベースの説明
出典:Wikipedia
出典:『Wikipedia』 (2011/06/28 04:32 UTC 版)
In molecular biology, platelet-derived growth factor (PDGF) is one of the numerous growth factors, or proteins that regulate cell growth and division. In particular, it plays a significant role in blood vessel formation (angiogenesis), the growth of blood vessels from already-existing blood vessel tissue. Uncontrolled angiogenesis is a characteristic of cancer. In chemical terms, platelet-derived growth factor is dimeric glycoprotein composed of two A (-AA) or two B (-BB) chains or a combination of the two (-AB).