出典:Wiktionary
polymyxa + -in, from Bacillus polymyxa, from which the antibiotic was isolated.
polymyxin (複数形 polymyxins)
出典:Wikipedia
出典:『Wikipedia』 (2011/05/01 18:08 UTC 版)
Polymyxins are antibiotics, with a general structure consisting of a cyclic peptide with a long hydrophobic tail. They disrupt the structure of the bacterial cell membrane by interacting with its phospholipids. They are produced by the Gram-positive bacterium Bacillus polymyxa and are selectively toxic for Gram-negative bacteria due to their specificity for the lipopolysaccharide molecule that exists within many Gram-negative outer membranes.
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