出典:Wiktionary
semaxanib (uncountable)
出典:Wikipedia
出典:『Wikipedia』 (2011/07/31 03:53 UTC 版)
Semaxanib (proposed INN, also semaxinib or SU5416) is a drug intended for use in the treatment of cancer. It is still at an experimental stage and as such has not yet received a licence for use on human patients (except in the setting of a clinical trial). Semaxanib is a potent and selective synthetic inhibitor of the Flk-1/KDR vascular endothelial growth factor (VEGF) receptor tyrosine kinase. It targets the VEGF pathway, and both in vivo and in vitro studies have demonstrated antiangiogenic potential.