nitazeneとは 意味・読み方・使い方

名詞

nitazene (countable and uncountable, plural nitazenes)

1. (uncountable, organic chemistry) A synthetic opioid derived from 2-benzylbenzimidazole.
2. (countable, organic chemistry) Any of a group of potent synthetic opioids with a structure related to nitazene, never approved for clinical use but manufactured as illicit drugs or adulterants thereof.

   Hyponyms: butonitazene, clonitazene, etonitazene, isotonitazene, metonitazene, protonitazene

   Coordinate terms: (adulterants) fentanyl (opioid); xylazine (anesthetic)

   • 2021, Marthe M. VandeputteKatleen Van Uytfangheet al., “Synthesis, Chemical Characterization, and μ‑Opioid Receptor Activity Assessment of the Emerging Group of “Nitazene” 2‑Benzylbenzimidazole Synthetic Opioids”, in ACS Chemical Neuroscience, volume 12, number 7, →DOI, page 1241:

     Several 2-benzylbenzimidazole opioids (also referred to as “nitazenes”) recently emerged on the illicit market. […] MOR activity determination confirmed that nitazenes are generally highly active, with potencies and efficacies of several analogues exceeding that of fentanyl.

Further reading

• nitazenes on Wikipedia.Wikipedia