| human | 遺伝子名 | CCL16 |
| 同義語(エイリアス) | LEC; Monotactin-1; Chemokine CC-4; Small inducible cytokine A16 precursor; Mtn-1; chemokine (C-C motif) ligand 16; CKb12; SCYA16; NCC-4; LCC-1; MTN-1; LMC; Lymphocyte and monocyte chemoattractant; MGC117051; SCYL4; NCC4; HCC-4; IL-10-inducible chemokine; Chemokine LEC; ILINCK; Liver-expressed chemokine | |
| SWISS-PROTのID | SWISS-PROT:O15467 | |
| EntrezGeneのID | EntrezGene:6360 | |
| その他のDBのID | HGNC:10614 |
本文中に表示されているデータベースの説明
出典:Wikipedia
出典:『Wikipedia』 (2010/07/25 01:11 UTC 版)
Chemokine (C-C motif) ligand 16 (CCL16) is a small cytokine belonging to the CC chemokine family that is known under several pseudonyms, including Liver-expressed chemokine (LEC) and Monotactin-1 (MTN-1). This chemokine is expressed by the liver, thymus, and spleen and is chemoattractive for monocytes and lymphocytes. Cellular expression of CCL16 can be strongly induced in monocytes by IL-10, IFN-γ and bacterial lipopolysaccharide. Its gene is located on chromosome 17, in humans, among a cluster of other CC chemokines. CCL16 elicits its effects on cells by interacting with cell surface chemokine receptors such as CCR1, CCR2, CCR5 and CCR8.