出典:Wikipedia
出典:『Wikipedia』 (2011/06/30 10:51 UTC 版)
Cardiovirus is a genus within the family Picornaviridae. The genus comprises two species: Encephalomyocarditis virus and Theilovirus. Encephalomyocarditis virus has only one serotype (of the same name), while Theilovirus consists of four viruses which are probably serologically distinct; these are Theiler's murine enceaphalomyelitis virus (TMEV), Vilyuisk human encephalomyelitis virus (VHEV), a Theiler-like virus (TLV) of rats (which has yet to be named) and Saffold virus (SAF-V). Cardioviruses infect vertebrates. The virion is non-enveloped and contains a strand of positive sense, single stranded RNA. The virion shows icosahedral symmetry and is around 30 nm in diameter. The 3’ end of the genome encodes a polyA tail while the 5’ end encodes a genome linked protein. A unique feature of this genus is the presence of the L* protein that is made out of frame from the polyprotein and is present in the DA subgroup of TMEV and is found to be important for the virus pathogenesis.