出典:Wikipedia
出典:『Wikipedia』 (2011/06/12 04:45 UTC 版)
Diazepam (
/daɪˈæzɨpæm/), first marketed as Valium (
/ˈvæliəm/) by Hoffmann-La Roche, is a benzodiazepine derivative drug. Diazepam is also marketed in Australia as Antenex. It is commonly used for treating anxiety, insomnia, seizures including status epilepticus, muscle spasms (such as in cases of tetanus), restless legs syndrome, alcohol withdrawal, benzodiazepine withdrawal and Ménière's disease. It may also be used before certain medical procedures (such as endoscopies) to reduce tension and anxiety, and in some surgical procedures to induce amnesia. It possesses anxiolytic, anticonvulsant, hypnotic, sedative, skeletal muscle relaxant, and amnestic properties. The pharmacological action of diazepam enhances the effect of the neurotransmitter GABA by binding to the benzodiazepine site on the GABAA receptor leading to central nervous system depression. Diazepam has also been used as a recreational drug.