She was deadly tired.
She was definitely tired.
She was green with envy
She felt blue.
She got the runs.
She was very weak.
She was very debilitated.
She is definitely tired.
She was taken with sickness [illness].
She had a difficult labor.
She's inclined to get tired easily.
She was worn out from overwork.
She had a nervous breakdown.
She was trembling with fear.