出典:Wikipedia
出典:『Wikipedia』 (2010/12/24 17:13 UTC 版)
Apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A, also known as APOBEC3A, is a gene of the APOBEC3 family found in at least in humans.. It is a cytidine deaminase with antiviral effects. While other members of the family such as APOBEC3G are believed to act by editing ssDNA or RNA by removing an amino group from cytidine, introducing a cytidine to uracil mutation, recent studies show that APOBEC3A inhibits parvoviruses by another mechanism. The cellular function of APOBEC3A is likely to be the destruction of foreign DNA through extensive deamination of cytosine .
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