出典:Wiktionary
iodo- + acetic acid
出典:Wikipedia
出典:『Wikipedia』 (2011/06/08 20:50 UTC 版)
Iodoacetic acid is a derivative of acetic acid. It is a toxic compound, because, like many alkyl halides, it is an alkylating agent. It reacts with cysteine residues in proteins. It is often used to modify SH-groups to prevent the re-formation of disulfide bonds after the reduction of cystine residues to cysteine during protein sequencing.