英和和英

出典:『Wikipedia』 (2011/08/02 12:01 UTC 版)

英語による解説

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In a nested case-control study, cases of a disease that occur in a defined cohort are identified and, for each, a specified number of matched controls is selected from among those in the cohort who have not developed the disease by the time of disease occurrence in the case. For many research questions, the nested case-control design potentially offers impressive reductions in costs and efforts of data collection and analysis compared with the full cohort approach, with relatively minor loss in statistical efficiency (see restricted randomization). The nested case-control design is particularly advantageous for studies of biologic precursors of disease.