出典:Wiktionary
出典:Wikipedia
出典:『Wikipedia』 (2010/12/31 08:40 UTC 版)
Siglecs, short for sialic acid binding Ig-like lectins are cell surface receptors and members of the immunoglobulin superfamily (IgSF) that recognize sugars. Their ability to recognize carbohydrates using an immunoglobulin domain places them in the group of I-type (Ig-type) lectins. They are transmembrane proteins that contain an N-terminal V-like immunoglobulin (IgV) domain that binds sialic acid and a variable number of C2-type Ig (IgC2) domains.