a drug used to prevent the rejection of organ and bone marrow transplants by the body. sirolimus is an antibiotic that blocks a protein involved in cell division and inhibits the growth and function of certain t cells of the immune system that are involved in the body's rejection of foreign tissues and organs. it is a type of immunosuppressant and a type of serine/threonine kinase inhibitor. sirolimus was previously called rapamycin. also called rapamune.
出典:Wikipedia
出典:『Wikipedia』 (2011/06/09 09:34 UTC 版)
Sirolimus (INN/USAN), also known as rapamycin, is an immunosuppressant drug used to prevent rejection in organ transplantation; it is especially useful in kidney transplants. A macrolide, sirolimus was first discovered as a product of the bacterium Streptomyces hygroscopicus in a soil sample from Easter Island — an island also known as Rapa Nui, hence the name. It is marketed under the trade name Rapamune by Wyeth.