出典:Wikipedia
出典:『Wikipedia』 (2011/03/19 16:52 UTC 版)
Complementarity determining regions (CDRs) are regions within antibodies (also known as immunoglobulins) or T cell receptors where these proteins complement an antigen's shape. Thus, CDRs determine the protein's affinity and specificity for specific antigens. The CDRs are the most variable part of the molecule, and contribute to the diversity of these molecules, allowing the antibody and the T cell receptor to recognize a vast repertoire of antigens.