human | 遺伝子名 | Constitutive androstane receptor |
同義語(エイリアス) | CAR-SV9; MB67; CAR-SV12; Constitutive activator of retinoid response; CAR1; CAR-SV17; nuclear receptor subfamily 1, group I, member 3; CAR-SV8; CAR-SV14; CAR-SV1; Constitutive active response; CAR-SV7; Orphan nuclear receptor NR1I3; CAR-SV19; CAR-SV15; CAR-SV18; CAR-SV13; CAR-SV10; Orphan nuclear receptor MB67; NR1I3; CAR-BETA; CAR-SV4; CAR-SV21; CAR-SV20; MGC97144; CAR-SV11; CAR-SV6 | |
SWISS-PROTのID | SWISS-PROT:Q14994 | |
EntrezGeneのID | EntrezGene:9970 | |
その他のDBのID | HGNC:7969 |
mouse | 遺伝子名 | Constitutive androstane receptor |
同義語(エイリアス) | AI551208; CAR2; MB67; CAR1; ESTM32; Orphan nuclear receptor MB67; nuclear receptor subfamily 1, group I, member 3; MGC107281; Car; AA209988; constitutively transactivates RAREs; Orphan nuclear receptor NR1I3; Care2; Nr1i3 | |
SWISS-PROTのID | SWISS-PROT:O35627 | |
EntrezGeneのID | EntrezGene:12355 | |
その他のDBのID | MGI:1346307 |
rat | 遺伝子名 | Constitutive androstane receptor |
同義語(エイリアス) | MGC108525; CAR; nuclear receptor subfamily 1, group I, member 3; strain Fischer nuclear receptor (CAR); Orphan nuclear receptor NR1I3; Nr1i3; nuclear receptor constitutive active receptor | |
SWISS-PROTのID | SWISS-PROT:Q9QUS1 | |
EntrezGeneのID | EntrezGene:65035 | |
その他のDBのID | RGD:621400 |
本文中に表示されているデータベースの説明
出典:Wikipedia
出典:『Wikipedia』 (2010/07/13 22:16 UTC 版)
The constitutive androstane receptor (CAR) also known as nuclear receptor subfamily 1, group I, member 3 is a protein that in humans is encoded by the NR1I3 gene. CAR is a member of the nuclear receptor superfamily and along with PXR functions as a sensor of endobiotic and xenobiotic substances and in response upregulates the expression of proteins responsible for the metabolism and excretion of these substances. Hence CAR (and PXR) are important in the detoxification of foreign substances such as drugs.